Overview on thioredoxin-interacting protein (TXNIP): A potential target for diabetes intervention

R Basnet, TB Basnet, BB Basnet… - Current Drug …, 2022 - ingentaconnect.com
Background: Diabetes mellitus (DM) is a common metabolic disorder characterized by a
persistent increment of blood glucose. Type 2 DM is characterized by insulin resistance and …

Potential of nanoencapsulated quercetin topical formulations in the management of diabetic foot ulcer

S Chaturvedi, S Agrawal, A Garg, V Rastogi - Revista Brasileira de …, 2023 - Springer
Diabetic foot ulcer originates due to peripheral neuropathy, immunosuppression, resistance
to infections, and peripheral arterial disease. The probability of lower limb amputation is …

[HTML][HTML] Hyperglycemia

MI Mouri, M Badireddy - StatPearls [Internet], 2023 - ncbi.nlm.nih.gov
Objectives: Describe the causes of hyperglycemia. Review the history and physical exam
findings expected in a patient with hyperglycemia. Summarize the treatment options for …

Vitamin D deficiency and diabetic retinopathy risk

S Navaei, S Nazemi, MH Emamian, H Hashemi… - Journal Français d' …, 2023 - Elsevier
Purpose Vitamin D deficiency may play an important role in the development and
progression of diabetic retinopathy. The present study aimed to assess the relationship …

A novel mortality risk score for emphysematous pyelonephritis: A multicenter study of the Global Research in the Emphysematous Pyelonephritis group

H Trujillo-Santamaría, JI Robles-Torres… - Current …, 2024 - journals.lww.com
Background Emphysematous pyelonephritis (EPN) is a necrotizing infection of the kidney
and the surrounding tissues associated with considerable mortality. We aimed to formulate a …

Establishment of hypertension risk nomograms based on physical fitness parameters for men and women: a cross-sectional study

Y Xu, Z Shi, D Sun, G Munivrana, M Liang… - Frontiers in …, 2023 - frontiersin.org
Objective This study aims to establish hypertension risk nomograms for Chinese male and
female adults, respectively. Method A series of questionnaire surveys, physical …

Animal models for induction of diabetes and its complications

F Qamar, S Sultana, M Sharma - Journal of Diabetes & Metabolic …, 2023 - Springer
Objectives Animal models are widely used to develop newer drugs for treatment of diabetes
and its complications. We conducted a systematic review to find various animal models to …

[PDF][PDF] Ethnopharmacology and phytochemistry-based review on the antimalarial potential of Acacia pennata (L.) Willd

JH Zothantluanga - Sci. Vis, 2020 - sciencevision.org
A protozoan infection called malaria is caused by Plasmodium parasites. In 2018, it infected
more than 228 million people and caused 405,000 fatalities. Worryingly, the present …

Role of DPP4 and DPP4i in Glucose Homeostasis and Cardiorenal Syndrome

SP Panda - Endocrine, Metabolic & Immune Disorders-Drug …, 2023 - ingentaconnect.com
The objective of the review led to the pursuit of adopting dipeptidyl peptidase-4 inhibitors
(DPP4i) as a novel pharmacotherapy in diabetes mellitus (DM) and cardiorenal syndrome …

Drug discovery

TJ Bateman - Atkinson's Principles of Clinical Pharmacology, 2022 - Elsevier
Drug discovery is the process of identifying and characterizing molecules with the potential
to safely modulate disease, with a goal to bring medicines that can improve the lives of …