Plant-microbial interaction: The mechanism and the application of microbial elicitor induced secondary metabolites biosynthesis in medicinal plants

I Chamkhi, T Benali, T Aanniz, N El Menyiy… - Plant Physiology and …, 2021 - Elsevier
Plants and microbes interact with each other via different chemical signaling pathways. At
the risophere level, the microbes can secrete molecules, called elicitors, which act on their …

Phenolic acids from plants: Extraction and application to human health

S Al Jitan, SA Alkhoori, LF Yousef - Studies in natural products chemistry, 2018 - Elsevier
Phenolic acids are biologically active molecules present in a wide range of edible and
nonedible plants. They have a commercial value in beauty, health, and medicinal industries …

[HTML][HTML] Hepatoprotective effects of rosmarinic acid: Insight into its mechanisms of action

TO Elufioye, S Habtemariam - Biomedicine & Pharmacotherapy, 2019 - Elsevier
Liver diseases such as hepatitis, fibrosis, cirrhosis, and hepatocellular carcinoma are one of
the major health challenges in the world and many conditions such as inadequate nutrition …

Best practices and progress in precision-cut liver slice cultures

L Dewyse, H Reynaert, LA van Grunsven - International journal of …, 2021 - mdpi.com
Thirty-five years ago, precision-cut liver slices (PCLS) were described as a promising tool
and were expected to become the standard in vitro model to study liver disease as they tick …

Evaluating the antifibrotic potency of galunisertib in a human ex vivo model of liver fibrosis

T Luangmonkong, S Suriguga… - British Journal of …, 2017 - Wiley Online Library
Background and Purpose Liver fibrosis is a major cause of liver‐related mortality and, so far,
no effective antifibrotic drug is available. Galunisertib, a TGF‐β receptor type I kinase …

Metabolic Profiling, Chemical Composition, Antioxidant Capacity, and In Vivo Hepato- and Nephroprotective Effects of Sonchus cornutus in Mice Exposed to Cisplatin

SS Elhady, RFA Abdelhameed, ET Mehanna… - Antioxidants, 2022 - mdpi.com
Sonchus cornutus (Asteraceae) is a wild. edible plant that represents a plentiful source of
polyphenolic compounds. For the first time, the metabolic analysis profiling demonstrated …

Human precision-cut liver slices as a model to test antifibrotic drugs in the early onset of liver fibrosis

IM Westra, HAM Mutsaers, T Luangmonkong, M Hadi… - Toxicology in Vitro, 2016 - Elsevier
Liver fibrosis is the progressive accumulation of connective tissue ultimately resulting in loss
of organ function. Currently, no effective antifibrotics are available due to a lack of reliable …

Antioxidant Effects of Satureja hortensis L. Attenuate the Anxiogenic Effect of Cisplatin in Rats

I Kumburovic, D Selakovic, T Juric… - Oxidative medicine …, 2019 - Wiley Online Library
Numerous adverse effects of cisplatin‐based therapy are usually accompanied by
enhanced oxidative damage and cell apoptosis in various tissues. Even neurotoxic …

Phenolic compounds as antioxidants to improve oxidative stability of menhaden oil-based structured lipid as butterfat analog

S Zhang, SA Willett, JR Hyatt, S Martini, CC Akoh - Food Chemistry, 2021 - Elsevier
Phenolic compounds, including propyl gallate, 1-o-galloylglycerol, ferulic, gallic, caffeic,
rosmarinic, and carnosic acids, tocopherols, and butylated hydroxytoluene (BHT), were …

Therapeutic Potential and Mechanisms of Rosmarinic Acid and the Extracts of Lamiaceae Plants for the Treatment of Fibrosis of Various Organs

YC Boo - Antioxidants, 2024 - mdpi.com
Fibrosis, which causes structural hardening and functional degeneration in various organs,
is characterized by the excessive production and accumulation of connective tissue …