[HTML][HTML] Exploring the multifactorial landscape of penile cancer: a comprehensive analysis of risk factors

U Amicuzi, M Grillo, M Stizzo, M Olivetta, S Tammaro… - Diagnostics, 2024 - mdpi.com
Penile cancer, while rare, is a critical public health issue due to its profound impact on
patients and the complexities of its management. The disease's multifactorial etiology …

Single-cell atlas of penile cancer reveals TP53 mutations as a driver of an aggressive phenotype, irrespective of human papillomavirus status, and provides clues for …

L Elst, G Philips, K Vandermaesen, A Bassez, F Lodi… - European Urology, 2024 - Elsevier
Background and objective TP53 loss-of-function (TP53LOF) mutations might be a driver of
poor prognosis and chemoresistance in both human papillomavirus (HPV)-independent …

Insights into the management of penile squamous cell carcinoma: from conventional approaches to emerging novel therapies

H Safa, C Mercinelli, PE Spiess, A Necchi… - Expert Opinion on …, 2024 - Taylor & Francis
Introduction Penile squamous cell carcinoma (PSCC), a rare genitourinary cancer, is
associated with poor outcomes due to limited treatment effectiveness, especially in …

Molecular characterization of metastatic penile squamous cell carcinoma in developing countries and its impact on clinical outcomes: LACOG 2018 translational study

FSM Monteiro, AM Alencar Junior… - The …, 2024 - academic.oup.com
Background Penile squamous cell carcinoma (PSCC) is a rare malignancy. However, in
developing countries the incidence rate is higher. The understanding of molecular …

Overview of Systemic Therapies in Penile Cancer

C Mercinelli, M Al Assaad, H Safa, PE Spiess… - Urologic …, 2024 - urologic.theclinics.com
Penile cancer (PC), although rare, poses significant challenges in both diagnosis and
treatment. 1, 2 Penile squamous cell carcinoma (PSCC) represents the most common …

Immune-based Therapies for Penile Cancer

M Al Assaad, H Safa, C Mercinelli, PE Spiess… - Urologic …, 2024 - urologic.theclinics.com
Penile carcinoma is a relatively rare malignancy with a prevalence of less than 1 per
100,000 men per year, with over 2000 new cases annually in the United States. 1, 2 Several …

Clinical Outcomes and Prognostic Factors in Patients With Penile Carcinoma: A Sub-Analysis From Meet-URO 23 (I-RARE) Registry Study

V Mollica, F Massari, M Maruzzo, D Bimbatti… - Clinical Genitourinary …, 2024 - Elsevier
Introduction Penile squamous cell carcinoma (PSCC) is a rare tumor with an aggressive
behavior. The Meet-URO 23/I-RARE registry includes rare genitourinary malignancies. We …

Real-World Outcomes in Patients with Advanced Penile Squamous Cell Carcinoma Receiving Immune Checkpoint Inhibitors: A Single Institution Experience

TZ Zhuang, S Goyal, KB Case… - Journal of …, 2024 - meridian.allenpress.com
Introduction Advanced penile squamous cell carcinoma (pSCC) is a rare and aggressive
malignancy with a poor prognosis and an unmet need for biomarkers. We performed a …

Pan-Cancer Genomic Characterization of Human Papillomavirus Associated Tumors

JR Holt - 2024 - search.proquest.com
Infection with high-risk human papillomavirus (HPV) accounts for nearly all cervical cancers
(CESC), a subset of other anogenital squamous cancers, and increasing rates of head and …

Mecanismos epigenéticos e variantes genômicas associados a infecção por HPV no câncer de pênis

RS Santos - 2024 - repositorio.ufc.br
RESUMO O câncer de pênis (CPE) é um tumor raro, que acomete cerca de 2% da
população masculina. O aumento da incidência da doença está relacionado às baixas …