[HTML][HTML] Functionalized liposomes for targeted breast cancer drug delivery

J Nel, K Elkhoury, É Velot, A Bianchi, S Acherar… - Bioactive materials, 2023 - Elsevier
Despite the exceptional progress in breast cancer pathogenesis, prognosis, diagnosis, and
treatment strategies, it remains a prominent cause of female mortality worldwide …

Membrane transporters in a human genome-scale metabolic knowledgebase and their implications for disease

S Sahoo, MK Aurich, JJ Jonsson, I Thiele - Frontiers in physiology, 2014 - frontiersin.org
Membrane transporters enable efficient cellular metabolism, aid in nutrient sensing, and
have been associated with various diseases, such as obesity and cancer. Genome-scale …

Recent development of biotin conjugation in biological imaging, sensing, and target delivery

WX Ren, J Han, S Uhm, YJ Jang, C Kang… - Chemical …, 2015 - pubs.rsc.org
Despite encouraging results from preliminary studies of anticancer therapies, the lack of
tumor specificity remains an important issue in the modern pharmaceutical industry. New …

Biotin functionalized PEGylated poly (amidoamine) dendrimer conjugate for active targeting of paclitaxel in cancer

SVK Rompicharla, P Kumari, H Bhatt, B Ghosh… - International journal of …, 2019 - Elsevier
In the current study, we employed poly (amidoamine)(PAMAM) dendrimers of generation 4
(G4) to deliver paclitaxel (PTX), a poorly soluble anti-cancer agent precisely to cancer cells …

Peptides and combination of peptides for use in immunotherapy against small cell lung cancer and other cancers

M Andrea, T Weinschenk, V Goldfinger… - US Patent …, 2019 - Google Patents
The present invention relates to peptides, proteins, nucleic acids and cells for use in
immunotherapeutic methods. In particular, the present invention relates to the immuno …

Peptides and combination of peptides for use in immunotherapy against small cell lung cancer and other cancers

M Andrea, T Weinschenk, V Goldfinger… - US Patent …, 2019 - Google Patents
The present invention relates to peptides, proteins, nucleic acids and cells for use in
immunotherapeutic methods. In particular, the present invention relates to the immuno …

Polymeric encapsulation of a ruthenium polypyridine complex for tumor targeted one-and two-photon photodynamic therapy

J Karges, J Li, L Zeng, H Chao… - ACS Applied Materials & …, 2020 - ACS Publications
Photodynamic therapy is a medical technique, which is gaining increasing attention to treat
various types of cancer. Among the investigated classes of photosensitizers (PSs), the use of …

Half‐Sandwich Ruthenium (II) Biotin Conjugates as Biological Vectors to Cancer Cells

MV Babak, D Plażuk, SM Meier… - … A European Journal, 2015 - Wiley Online Library
Ruthenium (II)–arene complexes with biotin‐containing ligands were prepared so that a
novel drug delivery system based on tumor‐specific vitamin‐receptor mediated endocytosis …

Biotin conjugates in targeted drug delivery: is it mediated by a biotin transporter, a yet to be identified receptor, or (an) other unknown mechanism (s)?

R Tripathi, A Guglani, R Ghorpade… - Journal of Enzyme …, 2023 - Taylor & Francis
Conjugation of drugs with biotin is a widely studied strategy for targeted drug delivery. The
structure–activity relationship (SAR) studies through H3-biotin competition experiments …

Multifunctional theranostic Pluronic mixed micelles improve targeted photoactivity of Verteporfin in cancer cells

DS Pellosi, IR Calori, LB de Paula, N Hioka… - Materials Science and …, 2017 - Elsevier
Nanotechnology development provides new strategies to treat cancer by integration of
different treatment modalities in a single multifunctional nanoparticle. In this scenario, we …