Neurodegenerative diseases (NDDs) are the primary cause of disabilities in the elderly
people. Growing evidence indicates that oxidative stress, mitochondrial dysfunction …

Sesamol is a lignan of sesame seeds and a natural phenolic molecule that has emerged as
a useful medical agent. Sesamol is a non-toxic phytoconstituent, which exerts certain …

Chlorogenic acid (CGA) is a naturally occurring polyphenolic acid from the family of
hydroxycinnamic acid, often found in green coffee extract and tea. CGA is chemically called …

It is considered a significant challenge to understand the neuronal cell death mechanisms
with a suitable cure for neurodegenerative disorders in the coming years. Calpains are one …

Background: Huntington's disease is an inherited autosomal dominant trait neuro-
degenerative disorder caused by changes (mutations) of a gene called huntingtin (htt) that is …

Objective: To propose a theoretical formulation of engeletin-nanostructured lipid
nanocarriers for improved delivery and increased bioavailability in treating Huntington's …

Fisetin (FS) is a bioactive flavonoid obtained mostly from apple and strawberry and
classified under the category of food supplements due to numerous pharmacological effects …

Quercetin (Qu), a dietary flavonoid, is obtained from many fruits and vegetables such as
coriander, broccoli, capers, asparagus, onion, figs, radish leaves, cranberry, walnuts, and …

Cancer, an intricate and multifaceted disease, is characterized by the uncontrolled
proliferation of cells that can lead to serious health complications and ultimately death …

Neurological disorders pose a great threat to social health and are a major cause for
mortality and morbidity. Effective drug development complemented with the improved drug …