The gut–liver axis and the intersection with the microbiome
In the past decade, an exciting realization has been that diverse liver diseases—ranging
from nonalcoholic steatohepatitis, alcoholic steatohepatitis and cirrhosis to hepatocellular …
from nonalcoholic steatohepatitis, alcoholic steatohepatitis and cirrhosis to hepatocellular …
Redox active cerium oxide nanoparticles: current status and burning issues
Research on cerium oxide nanoparticles (nanoceria) has captivated the scientific community
due to their unique physical and chemical properties, such as redox activity and oxygen …
due to their unique physical and chemical properties, such as redox activity and oxygen …
[HTML][HTML] Standardized extract of ginger ameliorates liver cancer by reducing proliferation and inducing apoptosis through inhibition oxidative stress/inflammation …
Ginger has been proposed as quite a promising candidate for cancer prevention. The
purpose of this study was to assess the chemo-preventive effects of ginger. Furthermore, this …
purpose of this study was to assess the chemo-preventive effects of ginger. Furthermore, this …
Gut microbiota in phytopharmacology: A comprehensive overview of concepts, reciprocal interactions, biotransformations and mode of actions
P Dey - Pharmacological research, 2019 - Elsevier
The dynamic and delicate interactions amongst intestinal microbiota, metabolome and
metabolism dictates human health and disease. In recent years, our understanding of gut …
metabolism dictates human health and disease. In recent years, our understanding of gut …
[HTML][HTML] GDF15 induces immunosuppression via CD48 on regulatory T cells in hepatocellular carcinoma
Z Wang, L He, W Li, C Xu, J Zhang… - … for immunotherapy of …, 2021 - ncbi.nlm.nih.gov
Background A better understanding of the molecular mechanisms that manifest in the
immunosuppressive tumor microenvironment (TME) is crucial for developing more …
immunosuppressive tumor microenvironment (TME) is crucial for developing more …
Combining crocin and sorafenib improves their tumor-inhibiting effects in a rat model of diethylnitrosamine-induced cirrhotic-hepatocellular carcinoma
Simple Summary Liver cancer represents one of the most lethal forms of cancer, with
hepatocellular carcinoma (HCC) accounting for the majority of its incidences and deaths …
hepatocellular carcinoma (HCC) accounting for the majority of its incidences and deaths …
Animal and organoid models of liver fibrosis
Y Bao, L Wang, H Pan, T Zhang, Y Chen, S Xu… - Frontiers in …, 2021 - frontiersin.org
Liver fibrosis refers to the process underlying the development of chronic liver diseases,
wherein liver cells are repeatedly destroyed and regenerated, which leads to an excessive …
wherein liver cells are repeatedly destroyed and regenerated, which leads to an excessive …
Therapeutic effects of crocin alone or in combination with sorafenib against hepatocellular carcinoma: in vivo & in vitro insights
This study investigated the therapeutic effects of the phytochemical crocin alone or in
combination with sorafenib both in rats chemically induced with hepatocellular carcinoma …
combination with sorafenib both in rats chemically induced with hepatocellular carcinoma …
6‐Gingerol, a Major Ingredient of Ginger Attenuates Diethylnitrosamine‐Induced Liver Injury in Rats through the Modulation of Oxidative Stress and Anti‐Inflammatory …
Diethylnitrosamine (DEN) is a well‐known hepatocarcinogen, and its oral administration
causes severe liver damage including cancer. DEN induces the pathogenesis of the liver …
causes severe liver damage including cancer. DEN induces the pathogenesis of the liver …
Nitrosamine contamination in pharmaceuticals: threat, impact, and control
B Tuesuwan, V Vongsutilers - Journal of Pharmaceutical Sciences, 2021 - Elsevier
Nitrosamine-contaminated medicinal products have raised safety concerns towards the use
of various drugs, not only valsartan and all tetrazole-containing angiotensin II receptor …
of various drugs, not only valsartan and all tetrazole-containing angiotensin II receptor …