Emerging cellular and molecular determinants of idiopathic pulmonary fibrosis
Idiopathic pulmonary fibrosis (IPF), the most common form of idiopathic interstitial
pneumonia, is a progressive, irreversible, and typically lethal disease characterized by an …
pneumonia, is a progressive, irreversible, and typically lethal disease characterized by an …
Clinical course and prediction of survival in idiopathic pulmonary fibrosis
B Ley, HR Collard, TE King Jr - American journal of respiratory and …, 2011 - atsjournals.org
Idiopathic pulmonary fibrosis (IPF) is a progressive, life-threatening, interstitial lung disease
of unknown etiology. The median survival of patients with IPF is only 2 to 3 years, yet some …
of unknown etiology. The median survival of patients with IPF is only 2 to 3 years, yet some …
Syndrome of combined pulmonary fibrosis and emphysema: an official ATS/ERS/JRS/ALAT research statement
Background: The presence of emphysema is relatively common in patients with fibrotic
interstitial lung disease. This has been designated combined pulmonary fibrosis and …
interstitial lung disease. This has been designated combined pulmonary fibrosis and …
Identifying an inciting antigen is associated with improved survival in patients with chronic hypersensitivity pneumonitis
ERF Pérez, JJ Swigris, AV Forssén, O Tourin… - Chest, 2013 - Elsevier
Background The cornerstone of hypersensitivity pneumonitis (HP) management is having
patients avoid the inciting antigen (IA). Often, despite an exhaustive search, an IA cannot be …
patients avoid the inciting antigen (IA). Often, despite an exhaustive search, an IA cannot be …
Citrullinated vimentin mediates development and progression of lung fibrosis
The mechanisms by which environmental exposures contribute to the pathogenesis of lung
fibrosis are unclear. Here, we demonstrate an increase in cadmium (Cd) and carbon black …
fibrosis are unclear. Here, we demonstrate an increase in cadmium (Cd) and carbon black …
Clinical features and outcomes in combined pulmonary fibrosis and emphysema in idiopathic pulmonary fibrosis
CJ Ryerson, T Hartman, BM Elicker, B Ley, JS Lee… - Chest, 2013 - Elsevier
Background Combined pulmonary fibrosis and emphysema (CPFE) is increasingly
recognized, but its prevalence and prognosis remain unclear. We sought to determine the …
recognized, but its prevalence and prognosis remain unclear. We sought to determine the …
Idiopathic pulmonary fibrosis: diagnosis, epidemiology and natural history
G Sgalla, A Biffi, L Richeldi - Respirology, 2016 - Wiley Online Library
Idiopathic pulmonary fibrosis (IPF) is a chronic, progressive fibrosing lung disorder of
unknown aetiology whose diagnosis involves the careful exclusion of secondary causes for …
unknown aetiology whose diagnosis involves the careful exclusion of secondary causes for …
Tobacco smoking is associated with combined pulmonary fibrosis and emphysema and worse outcomes in interstitial lung disease
D Douglas, L Keating, R Strykowski… - … of Physiology-Lung …, 2023 - journals.physiology.org
Tobacco smoking is an established cause of pulmonary disease whose contribution to
interstitial lung disease (ILD) is incompletely characterized. We hypothesized that compared …
interstitial lung disease (ILD) is incompletely characterized. We hypothesized that compared …
The aggregate index of systemic inflammation (AISI): A novel prognostic biomarker in idiopathic pulmonary fibrosis
Variable patterns of disease progression are typically observed in patients with idiopathic
pulmonary fibrosis (IPF). We sought to determine the prognostic capacity of blood cell count …
pulmonary fibrosis (IPF). We sought to determine the prognostic capacity of blood cell count …
[HTML][HTML] Oxidative stress in the pathogenesis of diffuse lung diseases: a review
E Bargagli, C Olivieri, D Bennett, A Prasse… - Respiratory …, 2009 - Elsevier
Oxidative stress is an imbalance between oxidants (reactive oxygen and nitrogen species)
and antioxidants that may affect lipids, DNA, carbohydrates and proteins. The lung is …
and antioxidants that may affect lipids, DNA, carbohydrates and proteins. The lung is …