Emerging cellular and molecular determinants of idiopathic pulmonary fibrosis

THG Phan, P Paliogiannis, GK Nasrallah… - Cellular and Molecular …, 2021 - Springer
Idiopathic pulmonary fibrosis (IPF), the most common form of idiopathic interstitial
pneumonia, is a progressive, irreversible, and typically lethal disease characterized by an …

Clinical course and prediction of survival in idiopathic pulmonary fibrosis

B Ley, HR Collard, TE King Jr - American journal of respiratory and …, 2011 - atsjournals.org
Idiopathic pulmonary fibrosis (IPF) is a progressive, life-threatening, interstitial lung disease
of unknown etiology. The median survival of patients with IPF is only 2 to 3 years, yet some …

Syndrome of combined pulmonary fibrosis and emphysema: an official ATS/ERS/JRS/ALAT research statement

V Cottin, M Selman, Y Inoue, AW Wong… - American journal of …, 2022 - atsjournals.org
Background: The presence of emphysema is relatively common in patients with fibrotic
interstitial lung disease. This has been designated combined pulmonary fibrosis and …

Identifying an inciting antigen is associated with improved survival in patients with chronic hypersensitivity pneumonitis

ERF Pérez, JJ Swigris, AV Forssén, O Tourin… - Chest, 2013 - Elsevier
Background The cornerstone of hypersensitivity pneumonitis (HP) management is having
patients avoid the inciting antigen (IA). Often, despite an exhaustive search, an IA cannot be …

Citrullinated vimentin mediates development and progression of lung fibrosis

FJ Li, R Surolia, H Li, Z Wang, G Liu… - Science translational …, 2021 - science.org
The mechanisms by which environmental exposures contribute to the pathogenesis of lung
fibrosis are unclear. Here, we demonstrate an increase in cadmium (Cd) and carbon black …

Clinical features and outcomes in combined pulmonary fibrosis and emphysema in idiopathic pulmonary fibrosis

CJ Ryerson, T Hartman, BM Elicker, B Ley, JS Lee… - Chest, 2013 - Elsevier
Background Combined pulmonary fibrosis and emphysema (CPFE) is increasingly
recognized, but its prevalence and prognosis remain unclear. We sought to determine the …

Idiopathic pulmonary fibrosis: diagnosis, epidemiology and natural history

G Sgalla, A Biffi, L Richeldi - Respirology, 2016 - Wiley Online Library
Idiopathic pulmonary fibrosis (IPF) is a chronic, progressive fibrosing lung disorder of
unknown aetiology whose diagnosis involves the careful exclusion of secondary causes for …

Tobacco smoking is associated with combined pulmonary fibrosis and emphysema and worse outcomes in interstitial lung disease

D Douglas, L Keating, R Strykowski… - … of Physiology-Lung …, 2023 - journals.physiology.org
Tobacco smoking is an established cause of pulmonary disease whose contribution to
interstitial lung disease (ILD) is incompletely characterized. We hypothesized that compared …

The aggregate index of systemic inflammation (AISI): A novel prognostic biomarker in idiopathic pulmonary fibrosis

A Zinellu, C Collu, M Nasser, P Paliogiannis… - Journal of Clinical …, 2021 - mdpi.com
Variable patterns of disease progression are typically observed in patients with idiopathic
pulmonary fibrosis (IPF). We sought to determine the prognostic capacity of blood cell count …

[HTML][HTML] Oxidative stress in the pathogenesis of diffuse lung diseases: a review

E Bargagli, C Olivieri, D Bennett, A Prasse… - Respiratory …, 2009 - Elsevier
Oxidative stress is an imbalance between oxidants (reactive oxygen and nitrogen species)
and antioxidants that may affect lipids, DNA, carbohydrates and proteins. The lung is …