History and progress of hypotheses and clinical trials for Alzheimer's disease

PP Liu, Y Xie, XY Meng, JS Kang - Signal transduction and targeted …, 2019 - nature.com
Alzheimer's disease (AD) is a neurodegenerative disease characterized by progressive
memory loss along with neuropsychiatric symptoms and a decline in activities of daily life. Its …

Heart disease and stroke statistics—2019 update: a report from the American Heart Association

EJ Benjamin, P Muntner, A Alonso, MS Bittencourt… - Circulation, 2019 - Am Heart Assoc
Summary Each year, the American Heart Association (AHA), in conjunction with the National
Institutes of Health and other government agencies, brings together in a single document the …

A 2022 update on the epidemiology of obesity and a call to action: as its twin COVID-19 pandemic appears to be receding, the obesity and dysmetabolism pandemic …

C Boutari, CS Mantzoros - Metabolism, 2022 - Elsevier
The WHO just released in May 2022 a report on the state of the obesity pandemic in Europe,
stating that 60% of citizens in the area of Europe are either overweight or obese, and …

The epidemiology of obesity

YC Chooi, C Ding, F Magkos - Metabolism, 2019 - Elsevier
Obesity is a complex multifactorial disease. The worldwide prevalence of overweight and
obesity has doubled since 1980 to an extent that nearly a third of the world's population is …

Lipid metabolism and Alzheimer's disease: clinical evidence, mechanistic link and therapeutic promise

F Yin - The FEBS journal, 2023 - Wiley Online Library
Alzheimer's disease (AD) is an ageassociated neurodegenerative disorder with
multifactorial etiology, intersecting genetic and environmental risk factors, and a lack of …

2018 Alzheimer's disease facts and figures

Alzheimer's Association - Alzheimer's & Dementia, 2018 - Elsevier
This article describes the public health impact of Alzheimer's disease (AD), including
incidence and prevalence, mortality and morbidity, costs of care, and the overall impact on …

Heart disease and stroke statistics—2018 update: a report from the American Heart Association

EJ Benjamin, SS Virani, CW Callaway… - Circulation, 2018 - Am Heart Assoc
Summary Each year, the American Heart Association (AHA), in conjunction with the Centers
for Disease Control and Prevention, the National Institutes of Health, and other government …

Global, regional, and national burden of Alzheimer's disease and other dementias, 1990–2016: a systematic analysis for the Global Burden of Disease Study 2016

E Nichols, CEI Szoeke, SE Vollset, N Abbasi… - The Lancet …, 2019 - thelancet.com
Background The number of individuals living with dementia is increasing, negatively
affecting families, communities, and health-care systems around the world. A successful …

Pathophysiological molecular mechanisms of obesity: a link between MAFLD and NASH with cardiovascular diseases

J Gutiérrez-Cuevas, A Santos… - International Journal of …, 2021 - mdpi.com
Obesity is now a worldwide epidemic ensuing an increase in comorbidities' prevalence,
such as insulin resistance, type 2 diabetes (T2D), metabolic dysfunction-associated fatty …

Heart disease and stroke statistics—2017 update: a report from the American Heart Association

EJ Benjamin, MJ Blaha, SE Chiuve, M Cushman… - circulation, 2017 - Am Heart Assoc
Summary Each year, the American Heart Association (AHA), in conjunction with the Centers
for Disease Control and Prevention, the National Institutes of Health, and other government …