Major histocompatibility complex genomics and human disease
J Trowsdale, JC Knight - Annual review of genomics and human …, 2013 - annualreviews.org
Over several decades, various forms of genomic analysis of the human major
histocompatibility complex (MHC) have been extremely successful in picking up many …
histocompatibility complex (MHC) have been extremely successful in picking up many …
A high-resolution HLA and SNP haplotype map for disease association studies in the extended human MHC
The proteins encoded by the classical HLA class I and class II genes in the major
histocompatibility complex (MHC) are highly polymorphic and are essential in self versus …
histocompatibility complex (MHC) are highly polymorphic and are essential in self versus …
PyPop update–a software pipeline for large‐scale multilocus population genomics
Population genetic statistics from multilocus genotype data inform our understanding of the
patterns of genetic variation and their implications for evolutionary studies, generally, and …
patterns of genetic variation and their implications for evolutionary studies, generally, and …
Genome-to-genome analysis highlights the effect of the human innate and adaptive immune systems on the hepatitis C virus
Outcomes of hepatitis C virus (HCV) infection and treatment depend on viral and host
genetic factors. Here we use human genome-wide genotyping arrays and new whole …
genetic factors. Here we use human genome-wide genotyping arrays and new whole …
[HTML][HTML] Immune system regulation and role of the human leukocyte antigen in posttraumatic stress disorder
S Katrinli, AK Smith - Neurobiology of Stress, 2021 - Elsevier
Posttraumatic stress disorder (PTSD) is a debilitating condition that adversely affect mental
and physical health. Recent studies have increasingly explored the role of the immune …
and physical health. Recent studies have increasingly explored the role of the immune …
MHC haplotype matching for unrelated hematopoietic cell transplantation
EW Petersdorf, M Malkki, TA Gooley, PJ Martin… - PLoS …, 2007 - journals.plos.org
Background Current criteria for the selection of unrelated donors for hematopoietic cell
transplantation (HCT) include matching for the alleles of each human leukocyte antigen …
transplantation (HCT) include matching for the alleles of each human leukocyte antigen …
Genetic diversity revealed in human faces
From an evolutionary perspective, human facial attractiveness is proposed to signal mate
quality. Using a novel approach to the study of the genetic basis of human preferences for …
quality. Using a novel approach to the study of the genetic basis of human preferences for …
A statistical method for predicting classical HLA alleles from SNP data
S Leslie, P Donnelly, G McVean - The American Journal of Human …, 2008 - cell.com
Genetic variation at classical HLA alleles is a crucial determinant of transplant success and
susceptibility to a large number of infectious and autoimmune diseases. However, large …
susceptibility to a large number of infectious and autoimmune diseases. However, large …
HLA class I polymorphisms are associated with development of infectious mononucleosis upon primary EBV infection
KA McAulay, CD Higgins, KF Macsween… - The Journal of …, 2007 - Am Soc Clin Investig
Infectious mononucleosis (IM) is an immunopathological disease caused by EBV that occurs
in young adults and is a risk factor for Hodgkin lymphoma (HL). An association between EBV …
in young adults and is a risk factor for Hodgkin lymphoma (HL). An association between EBV …
Multi-SNP analysis of MHC region: remarkable conservation of HLA-A1-B8-DR3 haplotype
TA Aly, E Eller, A Ide, K Gowan, SR Babu, HA Erlich… - Diabetes, 2006 - Am Diabetes Assoc
Technology has become available to cost-effectively analyze thousands of single nucleotide
polymorphisms (SNPs). We recently confirmed by genotyping a small series of class I alleles …
polymorphisms (SNPs). We recently confirmed by genotyping a small series of class I alleles …