The known unknowns: an overview of the state of blood-based protein biomarkers of mild traumatic brain injury
Blood-based protein biomarkers have revolutionized several fields of medicine by enabling
molecular level diagnosis, as well as monitoring disease progression and treatment efficacy …
molecular level diagnosis, as well as monitoring disease progression and treatment efficacy …
The immune system's role in the consequences of mild traumatic brain injury (concussion)
LN Verboon, HC Patel, AD Greenhalgh - Frontiers in immunology, 2021 - frontiersin.org
Mild traumatic brain injury (mild TBI), often referred to as concussion, is the most common
form of TBI and affects millions of people each year. A history of mild TBI increases the risk of …
form of TBI and affects millions of people each year. A history of mild TBI increases the risk of …
Characterizing head impact exposure in men and women during boxing and mixed martial arts
AE Jansen, M McGrath, S Samorezov… - … journal of sports …, 2021 - journals.sagepub.com
Background: The accumulation of subconcussive impacts has been implicated in permanent
neurological impairment. A gap in understanding the relationship between head impacts …
neurological impairment. A gap in understanding the relationship between head impacts …
Treatment with the vascular endothelial growth factor-A antibody, bevacizumab, has sex-specific effects in a rat model of mild traumatic brain injury
M Sun, TL Baker, CT Wilson, RD Brady… - Journal of Cerebral …, 2024 - journals.sagepub.com
Mild traumatic brain injury (mTBI) involves damage to the cerebrovascular system. Vascular
endothelial growth factor-A (VEGF-A) is an important modulator of vascular health and VEGF …
endothelial growth factor-A (VEGF-A) is an important modulator of vascular health and VEGF …
Blood-based biomarkers of repetitive, subconcussive blast overpressure exposure in the training environment: a pilot study
DV Agoston, J McCullough, R Aniceto, IH Lin… - Neurotrauma …, 2022 - liebertpub.com
Because of their unknown long-term effects, repeated mild traumatic brain injuries (TBIs),
including the low, subconcussive ones, represent a specific challenge to healthcare …
including the low, subconcussive ones, represent a specific challenge to healthcare …
Targeting the cerebrovascular system: next-generation biomarkers and treatment for mild traumatic brain injury
TL Baker, DV Agoston, RD Brady, B Major… - The …, 2022 - journals.sagepub.com
The diagnosis, prognosis, and treatment of mild traumatic brain injuries (mTBIs), such as
concussions, are significant unmet medical issues. The kinetic forces that occur in mTBI …
concussions, are significant unmet medical issues. The kinetic forces that occur in mTBI …
Elevated serum interleukin-1β levels in male, but not female, collision sport athletes with a concussion history
It is increasingly reported that a history of concussion may be associated with chronic
deleterious consequences. While the pathophysiology that contributes to these …
deleterious consequences. While the pathophysiology that contributes to these …
Early preclinical plasma protein biomarkers of brain trauma are influenced by early seizures and levetiracetam
PG Saletti, WB Mowrey, W Liu, Q Li… - Epilepsia …, 2023 - Wiley Online Library
Objective We used the lateral fluid percussion injury (LFPI) model of moderate‐to‐severe
traumatic brain injury (TBI) to identify early plasma biomarkers predicting injury, early post …
traumatic brain injury (TBI) to identify early plasma biomarkers predicting injury, early post …
Concussion and long‐term cognitive function among rugby players—The BRAIN Study
Abstract Objective The BRAIN Study was established to assess the associations between
self‐reported concussions and cognitive function among retired rugby players. Methods …
self‐reported concussions and cognitive function among retired rugby players. Methods …
Decrease in plasma miR-27a and miR-221 after concussion in Australian football players
Introduction: Sports-related concussion (SRC) is a common form of brain injury that lacks
reliable methods to guide clinical decisions. MicroRNAs (miRNAs) can influence biological …
reliable methods to guide clinical decisions. MicroRNAs (miRNAs) can influence biological …