Liver regeneration: biological and pathological mechanisms and implications

GK Michalopoulos, B Bhushan - Nature reviews Gastroenterology & …, 2021 - nature.com
The liver is the only solid organ that uses regenerative mechanisms to ensure that the liver-
to-bodyweight ratio is always at 100% of what is required for body homeostasis. Other solid …

Tumor development and angiogenesis in adult brain tumor: glioblastoma

BK Ahir, HH Engelhard, SS Lakka - Molecular neurobiology, 2020 - Springer
Angiogenesis is the growth of new capillaries from the preexisting blood vessels.
Glioblastoma (GBM) tumors are highly vascularized tumors, and glioma growth depends on …

TGF-β signaling in control of cardiovascular function

MJ Goumans, P Ten Dijke - Cold Spring Harbor …, 2018 - cshperspectives.cshlp.org
Genetic studies in animals and humans indicate that gene mutations that functionally perturb
transforming growth factor β (TGF-β) signaling are linked to specific hereditary vascular …

[HTML][HTML] The dual role of TGFβ in human cancer: from tumor suppression to cancer metastasis

JC Neel, L Humbert, JJ Lebrun - International Scholarly Research …, 2012 - hindawi.com
The transforming growth factor-beta (TGFβ) superfamily encompasses widespread and
evolutionarily conserved polypeptide growth factors that regulate and orchestrate growth …

Liver regeneration

GK Michalopoulos - Journal of cellular physiology, 2007 - Wiley Online Library
Liver regeneration after partial hepatectomy is a very complex and well‐orchestrated
phenomenon. It is carried out by the participation of all mature liver cell types. The process is …

[HTML][HTML] Balancing the activation state of the endothelium via two distinct TGF‐β type I receptors

MJ Goumans, G Valdimarsdottir, S Itoh… - The EMBO …, 2002 - embopress.org
The generation of mice lacking specific components of the transforming growth factor‐β
(TGF‐β) signal tranduction pathway shows that TGF‐β is a key player in the development …

[HTML][HTML] It takes two: endothelial-perivascular cell cross-talk in vascular development and disease

M Sweeney, G Foldes - Frontiers in cardiovascular medicine, 2018 - frontiersin.org
The formation of new blood vessels is a crucial step in the development of any new tissue
both during embryogenesis and in vitro models as without sufficient perfusion the tissue will …

Biological roles of fibroblast growth factor-2

A Bikfalvi, S Klein, G Pintucci, DB Rifkin - Endocrine reviews, 1997 - academic.oup.com
Biological Roles of Fibroblast Growth Factor-2* | Endocrine Reviews | Oxford Academic
Skip to Main Content Advertisement Oxford Academic Journals Books Search Menu …

VEGF receptor signaling in tumor angiogenesis

G McMahon - The oncologist, 2000 - academic.oup.com
The growth of human tumors and development of metastases depend on the de novo
formation of blood vessels. The formation of new blood vessels is tightly regulated by …

Activin receptor-like kinase 1 modulates transforming growth factor-β1 signaling in the regulation of angiogenesis

SP Oh, T Seki, KA Goss, T Imamura… - Proceedings of the …, 2000 - National Acad Sciences
The activin receptor-like kinase 1 (ALK1) is a type I receptor for transforming growth factor-β
(TGF-β) family proteins. Expression of ALK1 in blood vessels and mutations of the ALK1 …