Traumatic, tumoral, and infectious bone defects are common in clinics, and create a big
burden on patient's families and society. Calcium phosphate (CaP)-based biomaterials have …

The cell microenvironment has emerged as a key determinant of cell behavior and function
in development, physiology, and pathophysiology. The extracellular matrix (ECM) within the …

The development, maintenance of healthy bone and regeneration of injured tissue in the
human body comprise a set of intricate and finely coordinated processes. However, an …

Regenerative medicine has sparked interest in potential strategies for bone repair. Bone
defects are widespread and could be caused by trauma, congenital malformations …

Microporosity has a critical role in improving the osteogenesis of scaffolds for bone tissue
engineering. Although the exact mechanism, by which it promotes new bone formation, is …

The stem cell/material interface is a complex, dynamic microenvironment in which the cell
and the material cooperatively dictate one another's fate: the cell by remodelling its …

Calcium phosphate ceramics (CPCs) have been widely used as biomaterials for the
regeneration of bone tissue because of their ability to induce osteoblastic differentiation in …

The discovery of osteoinductivity of calcium phosphate (Ca-P) ceramics has set an enduring
paradigm of conferring biological regenerative activity to materials with carefully designed …

Regenerative medicine leverages the innate potential of the human body to efficiently repair
and regenerate damaged tissues using engineered biomaterials. By designing responsive …

The qualities of polymer based biomaterials in facilitating bone regeneration process
through tissue engineering have attracted the attention of researchers. Biomaterials with …