Epilepsy priorities in Europe: A report of the ILAE‐IBE epilepsy advocacy Europe task force

M Baulac, H De Boer, C Elger, M Glynn… - …, 2015 - Wiley Online Library
Summary The European Forum on Epilepsy Research (ERF 2013), which took place in
Dublin, Ireland, on May 26–29, 2013, was designed to appraise epilepsy research priorities …

Concise review: prospects of bone marrow mononuclear cells and mesenchymal stem cells for treating status epilepticus and chronic epilepsy

S Agadi, AK Shetty - Stem Cells, 2015 - academic.oup.com
Mononuclear cells (MNCs) and mesenchymal stem cells (MSCs) derived from the bone
marrow and other sources have received significant attention as donor cells for treating …

Редактирование генома человека

ДВ Ребриков - Вестник Российского государственного …, 2016 - cyberleninka.ru
Быстро развивающиеся технологии редактирования генома из научно-
исследовательских лабораторий уверенно переходят в клиническую практику …

[HTML][HTML] Changing channels in pain and epilepsy: Exploiting ion channel gene therapy for disorders of neuronal hyperexcitability

A Snowball, S Schorge - FEBS letters, 2015 - Elsevier
Chronic pain and epilepsy together affect hundreds of millions of people worldwide. While
traditional pharmacotherapy provides essential relief to the majority of patients, a large …

Recent advancements to enhance the therapeutic efficacy of antiepileptic drugs

F Li, AI SINGH - Acta Pharmaceutica, 2021 - hrcak.srce.hr
Sažetak Epilepsy is a multifactorial neurological disorder characterized by recurrent or
unprovoked seizures. Over the past two decades, many new antiepileptic drugs (AEDs) …

The Krushinsky–Molodkina genetic rat strain as a unique experimental model of seizure states

II Poletaeva, ZA Kostyna, NM Surina… - Vavilov Journal of …, 2017 - vavilov.elpub.ru
The study of genetic mechanisms, which underlie normal and abnormal behavioral traits,
are important not only for fundamental knowledge of CNS function, but also for human well …

Human genome editing

DV Rebrikov - Bulletin of Russian State Medical University, 2016 - cyberleninka.ru
The rapidly evolving genome editing techniques are steadily moving from research
laboratories to clinical practice. Fundamentally new methods of editing the genome of …

Генетическая линия крыс Крушинского–Молодкиной как уникальная экспериментальная модель судорожных состояний

ИИ Полетаева, ЗА Костына, НМ Сурина… - … журнал генетики и …, 2017 - vavilov.elpub.ru
Аннотация Исследование генетических механизмов, лежащих в основе нормальных и
патологических признаков поведения животных, важно не только для общего …

[PDF][PDF] 药物基因组学在难治性癫痫早期诊断和治疗中的应用进展

冯海燕, 李筱瑜, 郑乃智 - 国际神经病学神经外科学杂志, 2014 - jinn.org.cn
难治性癫痫早期诊断与治疗均存在较大困难. 药物基因组学从基因水平揭示个体差异,
通过检测酶相关基因, 基因多态性协助难治性癫痫诊断, 通过检测抗癫痫药相关代谢酶基因多态 …

Transcriptional upregulation as novel gene therapy strategy for neurological disorder

Y Qiu - 2023 - discovery.ucl.ac.uk
Epilepsy remains one of the commonest serious neurological diseases. 30% of people with
epilepsy are refractory to pharmacological treatment, and surgical resection of the focal …