Kinetic modeling and parametric imaging with dynamic PET for oncological applications: general considerations, current clinical applications, and future perspectives
A Dimitrakopoulou-Strauss, L Pan… - European journal of …, 2021 - Springer
Dynamic PET (dPET) studies have been used until now primarily within research purposes.
Although it is generally accepted that the information provided by dPET is superior to that of …
Although it is generally accepted that the information provided by dPET is superior to that of …
PET parametric imaging: past, present, and future
Positron emission tomography (PET) is actively used in a diverse range of applications in
oncology, cardiology, and neurology. The use of PET in the clinical setting focuses on static …
oncology, cardiology, and neurology. The use of PET in the clinical setting focuses on static …
A high-resolution in vivo atlas of the human brain's serotonin system
The serotonin (5-hydroxytryptamine, 5-HT) system modulates many important brain
functions and is critically involved in many neuropsychiatric disorders. Here, we present a …
functions and is critically involved in many neuropsychiatric disorders. Here, we present a …
Assessment of 18F-PI-2620 as a biomarker in progressive supranuclear palsy
Importance Progressive supranuclear palsy (PSP) is a 4-repeat tauopathy. Region-specific
tau aggregates establish the neuropathologic diagnosis of definite PSP post mortem. Future …
tau aggregates establish the neuropathologic diagnosis of definite PSP post mortem. Future …
MHC matching improves engraftment of iPSC-derived neurons in non-human primates
The banking of human leukocyte antigen (HLA)-homozygous-induced pluripotent stem cells
(iPSCs) is considered a future clinical strategy for HLA-matched cell transplantation to …
(iPSCs) is considered a future clinical strategy for HLA-matched cell transplantation to …
Autologous transplant therapy alleviates motor and depressive behaviors in parkinsonian monkeys
Degeneration of dopamine (DA) neurons in the midbrain underlies the pathogenesis of
Parkinson's disease (PD). Supplement of DA via L-DOPA alleviates motor symptoms but …
Parkinson's disease (PD). Supplement of DA via L-DOPA alleviates motor symptoms but …
In vivo characterization and quantification of neurofibrillary tau PET radioligand 18F-MK-6240 in humans from Alzheimer disease dementia to young controls
Tau PET imaging has potential for elucidating changes in the deposition of
neuropathological tau aggregates that are occurring during the progression of Alzheimer …
neuropathological tau aggregates that are occurring during the progression of Alzheimer …
[HTML][HTML] Serotonin transporter: gene, genetic disorders, and pharmacogenetics
DL Murphy, A Lerner, G Rudnick… - Molecular …, 2004 - triggered.edina.clockss.org
The highly evolutionarily conserved serotonin transporter (SERT) regulates the entire
serotoninergic system and its receptors via mod-ulation of extracellular fluid serotonin …
serotoninergic system and its receptors via mod-ulation of extracellular fluid serotonin …
Cortical surface-based analysis reduces bias and variance in kinetic modeling of brain PET data
Exploratory (ie, voxelwise) spatial methods are commonly used in neuroimaging to identify
areas that show an effect when a region-of-interest (ROI) analysis cannot be performed …
areas that show an effect when a region-of-interest (ROI) analysis cannot be performed …
Image-derived input function for brain PET studies: many challenges and few opportunities
P Zanotti-Fregonara, K Chen, JS Liow… - Journal of Cerebral …, 2011 - journals.sagepub.com
Quantitative positron emission tomography (PET) brain studies often require that the input
function be measured, typically via arterial cannulation. Image-derived input function (IDIF) …
function be measured, typically via arterial cannulation. Image-derived input function (IDIF) …