Chemokines are a family of small cytokines, which guide a variety of immune/inflammatory
cells to the site of tumor in tumorigenesis. A dysregulated expression of chemokines is …

Muscle atrophy is caused by an imbalance in contractile protein synthesis and degradation
which can be triggered by various conditions including Type 2 Diabetes Mellitus (T2DM) …

Adipocytes secrete a variety of bioactive molecules that affect the insulin sensitivity of other
tissues. We now show that the abundance of monocyte chemoattractant protein–1 (MCP-1) …

Monocyte Chemoattractant Protein-1 (MCP-1) is the first discovered and most extensively
studied CC chemokine, and the amount of studies on its role in the etiologies of obesity-and …

Weight gain and obesity are major risk factors for conditions and diseases ranging from
insulin resistance and type 2 diabetes mellitus to atherosclerosis and the sequelae of …

The CC motif chemokine receptor–2 (CCR2) regulates monocyte and macrophage
recruitment and is necessary for macrophage-dependent inflammatory responses and the …

insulin because of insulin resistance would thus result in the activation of these
proinflammatory transcription factors and an increase in the expression of the corresponding …

There is a great deal of evidence suggesting an important role for systemic inflammation in
the pathogenesis of A lzheimer's disease. The role of systemic inflammation, and indeed …

Obesity and type 2 diabetes are characterized by decreased insulin sensitivity, elevated
concentrations of free fatty acids (FFAs), and increased macrophage infiltration in adipose …

Obesity induces an inflammation state that is implicated in many clinically important
complications, including insulin resistance, diabetes, atherosclerosis and non‐alcoholic fatty …