Progress in the development of TRPV1 small-molecule antagonists: Novel Strategies for pain management
K Zhu, L Wang, TT Liao, W Li, J Zhou, Y You… - European journal of …, 2023 - Elsevier
Transient receptor potential vanilloid 1 (TRPV1) channels are widely distributed in sensory
nerve endings, the central nervous system, and other tissues, functioning as ion channel …
nerve endings, the central nervous system, and other tissues, functioning as ion channel …
[HTML][HTML] Plant-derived natural products targeting ion channels for pain
S Goyal, S Goyal, AE Goins, SRA Alles - Neurobiology of Pain, 2023 - Elsevier
Chronic pain affects approximately one-fifth of people worldwide and reduces quality of life
and in some cases, working ability. Ion channels expressed along nociceptive pathways …
and in some cases, working ability. Ion channels expressed along nociceptive pathways …
Natural active ingredients and TRPV1 modulation: focus on key chemical moieties involved in ligand–target interaction
Diseases such as cancer, neurological pathologies and chronic pain represent currently
unmet needs. The existing pharmacotherapeutic options available for treating these …
unmet needs. The existing pharmacotherapeutic options available for treating these …
Effect of Arbutus andrachne L. methanolic leaf extract on TRPV1 function: Experimental and molecular docking studies
Currently used analgesics have several side effects urging the need for new natural sources
of therapeutics. Transient receptor potential vanilloid 1 (TRPV1) is a non-selective cation …
of therapeutics. Transient receptor potential vanilloid 1 (TRPV1) is a non-selective cation …
[HTML][HTML] Analgesic and anti-inflammatory effects of galangin: a potential pathway to inhibit transient receptor potential vanilloid 1 receptor activation
K Lin, D Fu, Z Wang, X Zhang, C Zhu - The Korean Journal of Pain, 2024 - ncbi.nlm.nih.gov
Background Galangin, commonly employed in traditional Chinese medicine for its diverse
medicinal properties, exhibits potential in treating inflammatory pain. Nevertheless, its …
medicinal properties, exhibits potential in treating inflammatory pain. Nevertheless, its …
[HTML][HTML] Role of Transient Receptor Potential Vanilloid 1 in Health and Disease
SM Jaffal - Journal of Exploratory Research in Pharmacology, 2023 - xiahepublishing.com
Transient receptor potential vanilloid 1 (TRPV1) channel is a non-selective cation channel
that plays a pivotal role in pain transduction. However, more than a pain sensor, it is …
that plays a pivotal role in pain transduction. However, more than a pain sensor, it is …
[PDF][PDF] Analgesic effect of neohesperidin is mediated by TRPV1 antagonism
OA Abdulwahed, BO Al-Najjar, MA Abbas… - Journal of Pharmacy & …, 2023 - jppres.com
Context: Transient receptor potential vanilloid type 1 (TRPV1) is a non-specific cation
channel. It is one of the most important targets in pain research. Aims: To evaluate new …
channel. It is one of the most important targets in pain research. Aims: To evaluate new …
[HTML][HTML] Neohesperidin as a TRPV1 antagonist
OA Abdulwahed, BO Al-Najjar, MA Abbas, M Alsalem - jppres.com
Context: Transient receptor potential vanilloid type 1 (TRPV1) is a non-specific cation
channel. It is one of the most important targets in pain research. Aims: To evaluate new …
channel. It is one of the most important targets in pain research. Aims: To evaluate new …