DNA repair systems play a critical role in maintaining the integrity and stability of the
genome, which mainly include base excision repair (BER), nucleotide excision repair (NER) …

Background The XRCC3 p. Thr241Met (rs861539) polymorphism has been extensively
studied for its association with glioma risk, but results remain conflicting. Therefore, we …

Colorectal cancer (CRC), as a result of a multistep process and under multiple factors, is one
of the most common life‐threatening cancers worldwide. To identify the “high risk” …

Oxidative damage has been implicated in the pathogenesis of colorectal cancer (CRC). The
base excision repair (BER) pathway is the major DNA repair pathway for oxidative DNA …

Genetic polymorphisms in homologous recombination repair genes cause an abnormal
development of cancerous cells. In the present study we evaluated the possibility of breast …

Aim The X-ray repair cross-complementing (XRCC) gene polymorphisms influence
esophageal carcinogenesis by altering the DNA repair capacity. The present study was …

Colorectal cancer (CRC) is the third most common carcinoma worldwide. Despite the
progress in screening and treatment, CRC remains a leading cause of cancer-related …

Aim: Glioma cancer is the most common type of adult brain tumor. Recent genome-wide
association studies (GWAS) have identified various new susceptibility regions and here we …

The T241M polymorphism in the X-ray cross-complementing group 3 (XRCC3) had been
implicated in cancer susceptibility. The previous published data on the association between …

AIM: To study the association between four base excision repair gene polymorphisms and
colorectal cancer risk in a Chinese population. METHODS: Two hundred forty-seven …