[HTML][HTML] Global burden of Clostridium difficile infections: a systematic review and meta-analysis
E Balsells, T Shi, C Leese, I Lyell, J Burrows… - Journal of global …, 2019 - ncbi.nlm.nih.gov
Background Clostridium difficile is a leading cause of morbidity and mortality in several
countries. However, there are limited evidence characterizing its role as a global public …
countries. However, there are limited evidence characterizing its role as a global public …
Impact of microbial derived secondary bile acids on colonization resistance against Clostridium difficile in the gastrointestinal tract
JA Winston, CM Theriot - Anaerobe, 2016 - Elsevier
Clostridium difficile is an anaerobic, Gram positive, spore-forming bacillus that is the leading
cause of nosocomial gastroenteritis. Clostridium difficile infection (CDI) is associated with …
cause of nosocomial gastroenteritis. Clostridium difficile infection (CDI) is associated with …
Clostridium difficile infection: an epidemiology update
AC De Roo, SE Regenbogen - Clinics in colon and rectal …, 2020 - thieme-connect.com
Clostridium (reclassified as “Clostridioides”) difficile infection (CDI) is a healthcare-
associated infection and significant source of potentially preventable morbidity, recurrence …
associated infection and significant source of potentially preventable morbidity, recurrence …
Ursodeoxycholic acid (UDCA) mitigates the host inflammatory response during Clostridioides difficile infection by altering gut bile acids
Clostridioides difficile infection (CDI) is associated with increasing morbidity and mortality
posing an urgent threat to public health. Recurrence of CDI after successful treatment with …
posing an urgent threat to public health. Recurrence of CDI after successful treatment with …
Reuterin disrupts Clostridioides difficile metabolism and pathogenicity through reactive oxygen species generation
Antibiotic resistance is one of the world's greatest public health challenges and adjunct
probiotic therapies are strategies that could lessen this burden. Clostridioides difficile …
probiotic therapies are strategies that could lessen this burden. Clostridioides difficile …
Low Risk of Primary Clostridium difficile Infection With Tetracyclines: A Systematic Review and Metaanalysis
Background The choice of antibiotics for systemic infections in patients with a high risk of
Clostridium difficile infection (CDI) remains a clinical practice dilemma. Although some …
Clostridium difficile infection (CDI) remains a clinical practice dilemma. Although some …
[HTML][HTML] Rapid diagnostics for bloodstream infections: a primer for infection preventionists
CE Edmiston, R Garcia, M Barnden, B DeBaun… - American journal of …, 2018 - Elsevier
Accurate and rapid antimicrobial susceptibility testing with pathogen identification in
bloodstream infections is critical to life results for early sepsis intervention. Advancements in …
bloodstream infections is critical to life results for early sepsis intervention. Advancements in …
Omadacycline gut microbiome exposure does not induce Clostridium difficile proliferation or toxin production in a model that simulates the proximal, medial, and distal …
IB Moura, AM Buckley, D Ewin… - Antimicrobial agents …, 2019 - Am Soc Microbiol
ABSTRACT A clinically reflective model of the human colon was used to investigate the
effects of the broad-spectrum antibiotic omadacycline on the gut microbiome and the …
effects of the broad-spectrum antibiotic omadacycline on the gut microbiome and the …
Hospital-level high-risk antibiotic use in relation to hospital-associated Clostridioides difficile infections: retrospective analysis of 2016–2017 data from US hospitals
YP Tabak, A Srinivasan, CY Kalvin… - Infection Control & …, 2019 - cambridge.org
Objective: Antibiotics are widely used by all specialties in the hospital setting. We evaluated
previously defined high-risk antibiotic use in relation to Clostridioides difficile infections …
previously defined high-risk antibiotic use in relation to Clostridioides difficile infections …
Association of SARS-CoV-2 status and antibiotic-resistant bacteria with inadequate empiric therapy in hospitalized patients: a US multicenter cohort evaluation (July …
KA Bauer, LA Puzniak, KC Yu, KP Klinker… - BMC Infectious …, 2023 - Springer
Background Antibiotic usage and antibiotic resistance (ABR) patterns changed during the
COVID-19 pandemic. Inadequate empiric antibiotic therapy (IET) is a significant public …
COVID-19 pandemic. Inadequate empiric antibiotic therapy (IET) is a significant public …