The increasing commercial demand for L-carnitine has led to a multiplication of efforts to
improve its production with bacteria. The use of different cell environments, such as growing …

The state of the art tools for modeling metabolism, typically used in the domain of metabolic
engineering, were reviewed. The tools considered are stoichiometric network analysis …

l-Carnitine is essential in the intermediary metabolism of eukaryotes and is involved in the β-
oxidation of medium-and long-chain fatty acids; thus, it has applications for medicinal …

l-Carnitine is a bioactive compound derived from l-lysine and S-adenosyl-l-methionine,
which is closely associated with the transport of long-chain fatty acids in the intermediary …

Recently we proposed that the antineoplastic properties observed in vivo for alkyl-
lysophospholipid and alkylphosphocholine analogues are a direct consequence of the …

The aim of this work was to understand the steps controlling the biotransformation of
trimethylammonium compounds into l (-)-carnitine by Escherichia coli. The high-cell density …

Pulse experiments in continuous‐culture are a valuable tool in microbial physiology
research. However, inferences become difficult when the cell response is followed by …

L-(−)-carnitine can be synthesized from waste bioprecursors in the form of crotonobetaine.
Such biotransformation is carried out in E. coli by the enzymes encoded by operons …

摘要对酶转化法制备L-肉碱的菌种选育, 工艺优化, 合成代谢途径及下游技术等方面的研究进展
进行综述, 并由此提出, 提高以巴豆甜菜碱为前体的酶转化法的转化率, 获得L …

L‐carnitine, also known as vitamin BT, plays a key role in eukaryotes in the metabolism of
fats and other relevant physiological processes. In prokaryotes and plants, it is used as …