Remote ischemic conditioning

G Heusch, HE Bøtker, K Przyklenk, A Redington… - Journal of the American …, 2015 - jacc.org
In remote ischemic conditioning (RIC), brief, reversible episodes of ischemia with
reperfusion in one vascular bed, tissue, or organ confer a global protective phenotype and …

Interaction of risk factors, comorbidities, and comedications with ischemia/reperfusion injury and cardioprotection by preconditioning, postconditioning, and remote …

P Ferdinandy, DJ Hausenloy, G Heusch… - Pharmacological …, 2014 - Elsevier
Abstract Pre-, post-, and remote conditioning of the myocardium are well described adaptive
responses that markedly enhance the ability of the heart to withstand a prolonged …

Time to give up on cardioprotection? A critical appraisal of clinical studies on ischemic pre-, post-, and remote conditioning

G Heusch, T Rassaf - Circulation research, 2016 - Am Heart Assoc
The mortality from acute myocardial infarction (AMI) remains significant, and the prevalence
of post-myocardial infarction heart failure is increasing. Therefore, cardioprotection beyond …

Cardiac protective effects of remote ischaemic preconditioning in children undergoing tetralogy of fallot repair surgery: a randomized controlled trial

Q Wu, T Wang, S Chen, Q Zhou, H Li, N Hu… - European Heart …, 2018 - academic.oup.com
Aims Remote ischaemic preconditioning (RIPC) by inducing brief ischaemia in distant
tissues protects the heart against myocardial ischaemia-reperfusion injury (IRI) in children …

Ischaemic preconditioning for the reduction of renal ischaemia reperfusion injury

TP Menting, KE Wever… - Cochrane Database …, 2017 - cochranelibrary.com
Antecedentes La lesión por isquemia‐reperfusión puede provocar disfunción o insuficiencia
renal. El preacondicionamiento isquémico es un corto período de privación del suministro …

Remote ischemic conditioning and cardioprotection: a systematic review and meta-analysis of randomized clinical trials

S Le Page, T Bejan-Angoulvant, D Angoulvant… - Basic research in …, 2015 - Springer
Remote ischemic conditioning (RIC) represents an innovative cardioprotective method that
has been investigated in numerous clinical studies providing miscellaneous results. This …

Remote ischemic preconditioning in children undergoing cardiac surgery with cardiopulmonary bypass: a single‐center double‐blinded randomized trial

BW McCrindle, NA Clarizia, S Khaikin… - Journal of the …, 2014 - Am Heart Assoc
Background Remote ischemic preconditioning (RIPC) harnesses an innate defensive
mechanism that protects against inflammatory activation and ischemia‐reperfusion injury …

Remote ischemic preconditioning induces cardioprotective autophagy and signals through the IL-6-dependent JAK-STAT pathway

M Billah, A Ridiandries, UK Allahwala… - International Journal of …, 2020 - mdpi.com
Autophagy is a cellular process by which mammalian cells degrade and assist in recycling
damaged organelles and proteins. This study aimed to ascertain the role of autophagy in …

The role of remote ischemic preconditioning in organ protection after cardiac surgery: a meta-analysis

NABHM Yasin, P Herbison, P Saxena… - Journal of surgical …, 2014 - Elsevier
Background Remote ischemic preconditioning (RIPC) appears to protect distant organs from
ischemia–reperfusion injury. We undertook meta-analysis of clinical studies to evaluate the …

Egr-1 functions as a master switch regulator of remote ischemic preconditioning-induced cardioprotection

M Billah, A Ridiandries, BS Rayner… - Basic Research in …, 2020 - Springer
Despite improved treatment options myocardial infarction (MI) is still a leading cause of
mortality and morbidity worldwide. Remote ischemic preconditioning (RIPC) is a mechanistic …