Primary prevention of asthma: from risk and protective factors to targeted strategies for prevention
E von Mutius, HH Smits - The Lancet, 2020 - thelancet.com
Asthma is a complex disease that often starts in childhood. Genomic and environmental
factors as well as aberrant immune maturation early in life can contribute to the onset of …
factors as well as aberrant immune maturation early in life can contribute to the onset of …
Soil-transmitted helminth infections
PM Jourdan, PHL Lamberton, A Fenwick, DG Addiss - The lancet, 2018 - thelancet.com
More than a quarter of the world's population is at risk of infection with the soil-transmitted
helminths Ascaris lumbricoides, hookworm (Ancylostoma duodenale and Necator …
helminths Ascaris lumbricoides, hookworm (Ancylostoma duodenale and Necator …
[图书][B] The probiotic planet: Using life to manage life
J Lorimer - 2020 - books.google.com
Assesses a promising new approach to restoring the health of our bodies and our planet
Most of us are familiar with probiotics added to milk or yogurt to improve gastrointestinal …
Most of us are familiar with probiotics added to milk or yogurt to improve gastrointestinal …
Type 2 cytokines: mechanisms and therapeutic strategies
TA Wynn - Nature Reviews Immunology, 2015 - nature.com
Type 2 immune responses are defined by the cytokines interleukin-4 (IL-4), IL-5, IL-9 and IL-
13, which can either be host protective or have pathogenic activity. Type 2 immunity …
13, which can either be host protective or have pathogenic activity. Type 2 immunity …
The host microbiome regulates and maintains human health: a primer and perspective for non-microbiologists
Humans consider themselves discrete autonomous organisms, but recent research is
rapidly strengthening the appreciation that associated microorganisms make essential …
rapidly strengthening the appreciation that associated microorganisms make essential …
[HTML][HTML] Hookworm infection
Hookworms are soil-transmitted nematode parasites that can reside for many years in the
small intestine of their human hosts; Necator americanus is the predominant infecting …
small intestine of their human hosts; Necator americanus is the predominant infecting …
Parasite-microbiota interactions with the vertebrate gut: synthesis through an ecological lens
JM Leung, AL Graham, SCL Knowles - Frontiers in microbiology, 2018 - frontiersin.org
The vertebrate gut teems with a large, diverse, and dynamic bacterial community that has
pervasive effects on gut physiology, metabolism, and immunity. Under natural conditions …
pervasive effects on gut physiology, metabolism, and immunity. Under natural conditions …
Harnessing helminth-driven immunoregulation in the search for novel therapeutic modalities
Parasitic helminths have coevolved with humans over millennia, intricately refining and
developing an array of mechanisms to suppress or skew the host's immune system, thereby …
developing an array of mechanisms to suppress or skew the host's immune system, thereby …
[PDF][PDF] Chronic helminth infection and helminth‐derived egg antigens promote adipose tissue M2 macrophages and improve insulin sensitivity in obese mice
L Hussaarts, N García‐Tardón, L van Beek… - The FASEB …, 2015 - drive.google.com
Chronic low-grade inflammation associated with obesity contributes to insulin resistance
and type 2 diabetes. Helminth parasites are the strongest natural inducers of type 2 immune …
and type 2 diabetes. Helminth parasites are the strongest natural inducers of type 2 immune …
Regulatory T‐cells in helminth infection: induction, function and therapeutic potential
MPJ White, CM McManus, RM Maizels - Immunology, 2020 - Wiley Online Library
Helminth parasites infect an alarmingly large proportion of the world's population, primarily
within tropical regions, and their ability to down‐modulate host immunity is key to their …
within tropical regions, and their ability to down‐modulate host immunity is key to their …