Vaccines activate suitable immune responses to fight against diseases but can possess
limitations such as compromised efficacy and immunogenic responses, poor stability, and …

This review focuses on two formulation approaches, mucoadhesion and thermogelling,
intended for prolonging residence time on vaginal mucosa of medical devices or drug …

The vagina has been considered a potential drug administration route for centuries. Most of
the currently marketed and investigated vaginal formulations are composed with the use of …

Vaginal drug administration can improve prophylaxis and treatment of many conditions
affecting the female reproductive tract, including sexually transmitted diseases, fungal and …

Vesicular drug delivery systems have gained wide attention in the field of nanotechnology.
Among them proniosomes become the superior over other vesicular carriers. Proniosomes …

The vagina is a region of administration with a high contact surface to obtain local or
systemic effects. This anatomical area represents special interest for government health …

The vaginal delivery of various drugs is well described and its relevance established in
current medical practice. Alongside recent advances and achievements in the fields of …

Combining two or more antiretroviral drugs in one medical product is an interesting but
challenging strategy for developing topical anti-HIV microbicides. We developed a new …

Current drug therapy against infections is threatening to become obsolete due to the poor
physical, chemical, biological and pharmacokinetic properties of drugs, followed by high risk …

Nanopharmaceuticals have the potential to revolutionise medical treatment by permitting the
design of more potent, less toxic “smart” therapeutics, ultimately leading to personalised …