Glutamine is the most abundant circulating amino acid in blood and muscle and is critical for
many fundamental cell functions in cancer cells, including synthesis of metabolites that …

Arterial spin labeling (ASL) is a non-invasive MRI technique to measure cerebral blood flow
(CBF). This review provides a practical guide and overview of the clinical applications of …

Our understanding of the roles that the amino acids glutamate (Glu) and glutamine (Gln)
play in the mammalian central nervous system has increased rapidly in recent times. Many …

Localized proton magnetic resonance spectroscopy (MRS) of the human brain, first reported
more than 20 years ago, 1–3 is a mature methodology that is used clinically in many medical …

Oligodendroglioma are glial tumours, predominantly occurring in adults. Their hallmark
molecular feature is codeletion of the 1p and 19q chromosome arms, which is not only of …

Arterial spin labeling (ASL) imaging soon will be available as a routine clinical perfusion
imaging sequence for a significant number of MR imaging scanners. The ASL perfusion …

Purpose To explore the feasibility and diagnostic performance of radiomics based on
anatomical, diffusion and perfusion MRI in differentiating among glioma subtypes and …

Introduction The purpose of this study was to compare the non-invasive 3D pseudo-
continuous arterial spin labelling (PC ASL) technique with the clinically established dynamic …

Altered metabolism is a hallmark of cancer cells. Tumor cells rewire their metabolism to
support their uncontrolled proliferation by taking up nutrients from the microenvironment …

The revolution in cancer genomics has uncovered a variety of clinically relevant mutations in
primary brain tumours, creating an urgent need to develop non-invasive imaging biomarkers …