Opportunities and challenges for co-delivery nanomedicines based on combination of phytochemicals with chemotherapeutic drugs in cancer treatment

Q Gao, J Feng, W Liu, C Wen, Y Wu, Q Liao… - Advanced drug delivery …, 2022 - Elsevier
The therapeutic limitations such as insufficient efficacy, drug resistance, metastasis, and
undesirable side effects are frequently caused by the long duration monotherapy based on …

Nutritional values, beneficial effects, and food applications of broccoli (Brassica oleracea var. italica Plenck)

H Li, Y Xia, HY Liu, H Guo, XQ He, Y Liu, DT Wu… - Trends in Food Science …, 2022 - Elsevier
Abstract Background Broccoli (Brassica oleracea var. italica Plenck) is one of the most
common cruciferous vegetables in the world. Broccoli florets and sprouts are usually used …

The molecular basis and therapeutic aspects of cisplatin resistance in oral squamous cell carcinoma

Y Cheng, S Li, L Gao, K Zhi, W Ren - Frontiers in oncology, 2021 - frontiersin.org
Oral squamous cell carcinoma (OSCC) is a kind of malignant tumors with low survival rate
and prone to have early metastasis and recurrence. Cisplatin is an alkylating agent which …

Broccoli: A multi-faceted vegetable for health: An in-depth review of its nutritional attributes, antimicrobial abilities, and anti-inflammatory properties

RU Syed, SS Moni, MKB Break, WMA Khojali, M Jafar… - Antibiotics, 2023 - mdpi.com
Broccoli, Brassica oleracea var. italica, has recently gained considerable attention due to its
remarkable nutritional composition and numerous health benefits. In this review, the …

Anticancer activity of broccoli, its organosulfur and polyphenolic compounds

A Gasmi, A Gasmi Benahmed, M Shanaida… - Critical Reviews in …, 2024 - Taylor & Francis
The use of natural bioactive constituents from various food sources for anticancer purposes
has become increasingly popular worldwide. Broccoli (Brassica oleracea var. italica) is on …

Codelivery of phytochemicals with conventional anticancer drugs in form of nanocarriers

G Kumar, T Virmani, A Sharma, K Pathak - Pharmaceutics, 2023 - mdpi.com
Anticancer drugs in monotherapy are ineffective to treat various kinds of cancer due to the
heterogeneous nature of cancer. Moreover, available anticancer drugs possessed various …

Searching for the antioxidant, anti-inflammatory, and neuroprotective potential of natural food and nutritional supplements for ocular health in the mediterranean …

M Valero-Vello, C Peris-Martínez, JJ García-Medina… - Foods, 2021 - mdpi.com
Adherence to a healthy diet offers a valuable intervention to compete against the increasing
cases of ocular diseases worldwide, such as dry eye disorders, myopia progression …

Targeting cancer stem cells by nutraceuticals for cancer therapy

M Chu, C Zheng, C Chen, G Song, X Hu… - Seminars in cancer …, 2022 - Elsevier
Accumulating evidence has demonstrated that cancer stem cells (CSCs) play an essential
role in tumor progression and reoccurrence and drug resistance. Multiple signaling …

Harnessing Sulforaphane Potential as a Chemosensitizing Agent: A Comprehensive Review

BL Sailo, L Liu, S Chauhan, S Girisa, M Hegde, L Liang… - Cancers, 2024 - mdpi.com
Simple Summary Recent oncological research highlights the promising role of naturally
derived compounds in cancer prevention and treatment. Sulforaphane (SFN), a …

Research progress on the utilization technology of broccoli stalk, leaf resources, and the mechanism of action of its bioactive substances

L Yan, G Zhou, K Shahzad, H Zhang, X Yu… - Frontiers in Plant …, 2023 - frontiersin.org
Broccoli is a nutritious vegetable. It is high in protein, minerals, and vitamins. Also, it
possesses antioxidant activities and is beneficial to the human body. Due to its active effect …