The intestinal surface is constitutively exposed to diverse antigens, such as food antigens,
food-borne pathogens, and commensal microbes. Intestinal epithelial cells have developed …

The gastrointestinal tract is a specialized organ in which dynamic interactions between host
cells and the complex environment occur in addition to food digestion. Together with the …

Cellular Phenotype and Apoptosis: The function of epithelial tissues is the protection of the
organism from chemical, microbial, and physical challenges which is indispensable for …

The ability of epithelial cells to organize through cell–cell adhesion into a functioning
epithelium serves the purpose of a tight epithelial protective barrier. Contacts between …

Beside digesting nutrients and absorbing solutes and electrolytes, the intestinal epithelium
with its barrier function is in charge of a tightly controlled antigen trafficking from the …

The intestinal tract is lined by a single layer of columnar epithelial cells that forms a dynamic,
permeable barrier allowing for selective absorption of nutrients, while restricting access to …

Epithelial tight junctions (TJs) are the key structures regulating paracellular trafficking of
macromolecules. The TJ is multi-protein complex that forms a selective permeable seal …

Spermatogenesis is the cellular process by which spermatogonia develop into mature
spermatids within seminiferous tubules, the functional unit of the mammalian testis, under …

Recent evidence provides support for involvement of the microbiota-gut-brain axis in
Parkinson's disease (PD) pathogenesis. We propose that a pro-inflammatory intestinal …

The gastrointestinal epithelium forms the boundary between the body and external
environment. It effectively provides a selective permeable barrier that limits the permeation …