[HTML][HTML] Obesity-induced changes in human islet G protein-coupled receptor expression: Implications for metabolic regulation

P Atanes, T Ashik, SJ Persaud - Pharmacology & Therapeutics, 2021 - Elsevier
G protein-coupled receptors (GPCRs) are a large family of cell surface receptors that are the
targets for many different classes of pharmacotherapy. The islets of Langerhans are central …

[HTML][HTML] Metabolite G-protein coupled receptors in cardio-metabolic diseases

D Strassheim, T Sullivan, DC Irwin, E Gerasimovskaya… - Cells, 2021 - mdpi.com
G protein-coupled receptors (GPCRs) have originally been described as a family of
receptors activated by hormones, neurotransmitters, and other mediators. However, in …

The effect of Xuezhikang capsule on gene expression profile in brown adipose tissue of obese spontaneously hypertensive rats

S Zhang, Y Jiang, X Wang, H Zhang, P Gu… - Journal of …, 2023 - Elsevier
Ethnopharmacological relevance Obesity is a critical threat to global health, and brown
adipose tissue (BAT) is a potential target for the treatment of obesity and comorbidities …

Overexpressing the hydroxycarboxylic acid receptor 1 in mouse brown adipose tissue restores glucose tolerance and insulin sensitivity in diet-induced obese mice

HY Min, J Hwang, Y Choi… - American Journal of …, 2022 - journals.physiology.org
Interscapular brown adipose tissue (BAT) plays an important role in controlling glucose
homeostasis. Increased glucose entry and glycolysis in BAT result in lactate production and …

[HTML][HTML] GPCR-Mediated Regulation of Fuel and Energy Metabolism in Peripheral Tissues: Overexpressing the hydroxycarboxylic acid receptor 1 in mouse brown …

HY Min, J Hwang, Y Choi, YH Jo - American Journal of Physiology …, 2022 - ncbi.nlm.nih.gov
Interscapular brown adipose tissue (BAT) plays an important role in controlling glucose
homeostasis. Increased glucose entry and glycolysis in BAT result in lactate production and …

Loss of the brain-liver axis prevents hepatic steatosis in mice

J Hwang, J Okada, L Liu, JE Pessin, GJ Schwartz… - bioRxiv, 2023 - biorxiv.org
Hepatic lipid metabolism is regulated by the autonomic nervous system of the liver, with the
sympathetic innervation being extensively studied, while the parasympathetic efferent …

Ablation of parasympathetic cholinergic innervation of the liver prevents diet-induced obesity and hepatic steatosis in mice

J Hwang, J Okada, L Liu, JE Pessin, GJ Schwartz, Y Jo - 2023 - europepmc.org
The role of parasympathetic cholinergic innervation in hepatic lipid metabolism has been the
subject of considerable debate because of a lack of neuroanatomical studies. We …

[PDF][PDF] Revisión de literatura: Esteatosis hepática no alcohólica y formulación de una bebida de lactosuero y β-glucanos como propuesta para mejorar su daño

KB Calderón - 2021 - bdigital.zamorano.edu
La esteatosis hepática no alcohólica (EHNA) es una enfermedad caracterizada por la
acumulación de ácidos grasos y triglicéridos en el citoplasma de los hepatocitos, en …

[PDF][PDF] TANYA MÜLLER GARCÍA

ANAMM ACOSTA, R CASTILLO, HZ MEMBREÑO - bdigital.zamorano.edu
Non-alcoholic hepatic steatosis (NASH) is a disease characterized by the accumulation of
fatty acids and triglycerides in the cytoplasm of hepatocytes, in amounts greater than 5% of …

[引用][C] 乳酸/HCAR1 信号系统的生物学功能研究进展

帅念念, 周佳秀, 田绍文, 王波, 旷昕 - 临床与病理杂志, 2021