Engineering Anisotropy into Organized Nanoscale Matter
Programming the organization of discrete building blocks into periodic and quasi-periodic
arrays is challenging. Methods for organizing materials are particularly important at the …
arrays is challenging. Methods for organizing materials are particularly important at the …
Programmability and biomedical utility of intrinsically-disordered protein polymers
MC Giraldo-Castano, KA Littlejohn… - Advanced Drug Delivery …, 2024 - Elsevier
Intrinsically disordered proteins (IDPs) exhibit molecular-level conformational dynamics that
are functionally harnessed across a wide range of fascinating biological phenomena. The …
are functionally harnessed across a wide range of fascinating biological phenomena. The …
Proteininvbench: Benchmarking protein inverse folding on diverse tasks, models, and metrics
Protein inverse folding has attracted increasing attention in recent years. However, we
observe that current methods are usually limited to the CATH dataset and the recovery …
observe that current methods are usually limited to the CATH dataset and the recovery …
De novo design of allosterically switchable protein assemblies
Allosteric modulation of protein function, wherein the binding of an effector to a protein
triggers conformational changes at distant functional sites, plays a central part in the control …
triggers conformational changes at distant functional sites, plays a central part in the control …
Peptide bundlemer networks or lattices: controlling cross-linking and self-assembly using protein-like display of chemistry
Coiled-coil 'bundlemer'peptides were selectively modified with allyloxycarbonyl (alloc)-
protected lysine, a non-natural amino acid containing an alkene on its side chain. The …
protected lysine, a non-natural amino acid containing an alkene on its side chain. The …
Blueprinting extendable nanomaterials with standardized protein blocks
A wooden house frame consists of many different lumber pieces, but because of the
regularity of these building blocks, the structure can be designed using straightforward …
regularity of these building blocks, the structure can be designed using straightforward …
AlphaFold 3–Aided Design of DNA Motifs To Assemble into Triangles
Anusha, Z Zhang, J Li, H Zuo… - Journal of the American …, 2024 - ACS Publications
Self-assembly of biomolecules provides a powerful tool for a wide range of applications in
nanomedicine, biosensing and imaging, vaccines, computation, nanophotonics, etc. The key …
nanomedicine, biosensing and imaging, vaccines, computation, nanophotonics, etc. The key …
Beyond 25 years of biomedical innovation in nano-bioelectronics
Nano-bioelectronics, which blend the precision of nanotechnology with the complexity of
biological systems, are evolving with innovations such as silicon nanowires, carbon …
biological systems, are evolving with innovations such as silicon nanowires, carbon …
Biopharmaceutical drug delivery and phototherapy using protein crystals
Biopharmaceutical drugs, including proteins, peptides, and antibodies, are renowned for
their high specificity and efficacy, fundamentally transforming disease treatment paradigms …
their high specificity and efficacy, fundamentally transforming disease treatment paradigms …
Nanoparticle Superlattices with Nonequilibrium Crystal Shapes
Nanoparticle assembly is a material synthesis strategy that enables precise control of
nanoscale structural features. Concepts from traditional crystal growth research have been …
nanoscale structural features. Concepts from traditional crystal growth research have been …