Dopamine, immunity, and disease

B Channer, SM Matt, EA Nickoloff-Bybel, V Pappa… - Pharmacological …, 2023 - ASPET
The neurotransmitter dopamine is a key factor in central nervous system (CNS) function,
regulating many processes including reward, movement, and cognition. Dopamine also …

Neurotransmitters: The critical modulators regulating gut–brain axis

R Mittal, LH Debs, AP Patel, D Nguyen… - Journal of cellular …, 2017 - Wiley Online Library
Neurotransmitters, including catecholamines and serotonin, play a crucial role in
maintaining homeostasis in the human body. Studies on these neurotransmitters mainly …

Main active components of Jiawei Gegen Qinlian decoction protects against ulcerative colitis under different dietary environments in a gut microbiota-dependent …

Q Li, Y Cui, B Xu, Y Wang, F Lv, Z Li, H Li… - Pharmacological …, 2021 - Elsevier
As an effective drug against acute enteritis diarrhea, Gegen Qinlian decoction (GQD) has a
history of 2000 years. However, the potential molecular mechanism through which GQD …

[HTML][HTML] Where is dopamine and how do immune cells see it?: dopamine-mediated immune cell function in health and disease

SM Matt, PJ Gaskill - Journal of Neuroimmune Pharmacology, 2020 - Springer
Dopamine is well recognized as a neurotransmitter in the brain, and regulates critical
functions in a variety of peripheral systems. Growing research has also shown that …

[HTML][HTML] Neuroprotective strategies for retinal disease

MT Pardue, RS Allen - Progress in retinal and eye research, 2018 - Elsevier
Diseases that affect the eye, including photoreceptor degeneration, diabetic retinopathy, and
glaucoma, affect 11.8 million people in the US, resulting in vision loss and blindness. Loss of …

Immunomodulatory effects of dopamine in inflammatory diseases

Y Feng, Y Lu - Frontiers in immunology, 2021 - frontiersin.org
Dopamine (DA) receptor, a significant G protein-coupled receptor, is classified into two
families: D1-like (D1 and D5) and D2-like (D2, D3, and D4) receptor families, with further …

Berberine and inflammatory bowel disease: a concise review

S Habtemariam - Pharmacological research, 2016 - Elsevier
Berberine is the principal component of many popular medicinal plants (eg the genus
Berberis, Coptis and Hydrastis among others) with a history of thousands of years of usage …

[HTML][HTML] Dopamine, a co-regulatory component, bridges the central nervous system and the immune system

M Li, L Zhou, X Sun, Y Yang, C Zhang, T Wang… - Biomedicine & …, 2022 - Elsevier
Dopamine (DA) is a crucial neurotransmitter that plays an important role in maintaining
physiological function in human body. In the past, most studies focused on the relationship …

Angiotensin type 1 receptor activation promotes neuronal and glial alpha-synuclein aggregation and transmission

L Lage, AI Rodriguez-Perez, B Villar-Cheda… - npj Parkinson's …, 2024 - nature.com
The brain renin-angiotensin system (RAS) has been related to dopaminergic degeneration,
and high expression of the angiotensin II (AngII) type 1 receptor (AT1) gene is a marker of …

[HTML][HTML] Targeting the dopaminergic system in autoimmunity

PM Vidal, R Pacheco - Journal of Neuroimmune Pharmacology, 2020 - Springer
Dopamine has emerged as a fundamental regulator of inflammation. In this regard, it has
been shown that dopaminergic signalling pathways are key players promoting homeostasis …