Osteoarthritis (OA) is the most common type of degenerative joint disease which affects 7%
of the global population and more than 500 million people worldwide. One research frontier …

The temporomandibular joint (TMJ) is a specialized synovial joint that is crucial for the
movement and function of the jaw. TMJ osteoarthritis (TMJ OA) is the result of disc …

Hydrogels are a versatile category of biomaterials that have been widely applied in the fields
of biomedicine for the last several decades. The three-dimensional polymeric crosslinked …

The challenges for developing new pharmaceutical formulations based on natural and
synthetic polymers has led to innovation into the design of systems responsive …

Osteoarthritis (OA) is a degenerative joint disease that is characterized by inflammation of
the joints, degradation of cartilage, and the remodeling of other joint tissues. Due to the …

Purpose Thermosensitive in situ gels have been around for decades but only a few have
been translated into ophthalmic pharmaceuticals. The aim of this study was to combine the …

Rheumatoid arthritis (RA) and osteoarthritis (OA) are disabling musculoskeletal disorders
that affect joints and cartilage and may lead to bone degeneration. Conventional delivery of …

Murine macrophages activated by the Toll-like receptor 4 agonist lipopolysaccharide (LPS)
polarize to the M1 type by inducing proinflammatory marker proteins and changing their …

Injectable hydrogels are gaining prominence as a biocompatible, minimally invasive, and
adaptable platform for cartilage tissue engineering. Commencing with their synthesis, this …

Gels are semisolid, homogeneous systems with continuous or discrete therapeutic
molecules in a suitable lipophilic or hydrophilic three-dimensional network base. Innovative …