The neuroprotective effects of glucagon-like peptide 1 in Alzheimer's and Parkinson's disease: An in-depth review
N Reich, C Hölscher - Frontiers in neuroscience, 2022 - frontiersin.org
Currently, there is no disease-modifying treatment available for Alzheimer's and Parkinson's
disease (AD and PD) and that includes the highly controversial approval of the Aβ-targeting …
disease (AD and PD) and that includes the highly controversial approval of the Aβ-targeting …
[HTML][HTML] Into the groove: can rhythm influence Parkinson's disease?
Previous research has noted that music can improve gait in several pathological conditions,
including Parkinson's disease, Huntington's disease and stroke. Current research into …
including Parkinson's disease, Huntington's disease and stroke. Current research into …
Glycolytic metabolism, brain resilience, and Alzheimer's disease
X Zhang, N Alshakhshir, L Zhao - Frontiers in Neuroscience, 2021 - frontiersin.org
Alzheimer's disease (AD) is the most common form of age-related dementia. Despite
decades of research, the etiology and pathogenesis of AD are not well understood. Brain …
decades of research, the etiology and pathogenesis of AD are not well understood. Brain …
Roles of amyloid β-peptide-associated oxidative stress and brain protein modifications in the pathogenesis of Alzheimer's disease and mild cognitive impairment
DA Butterfield, T Reed, SF Newman… - Free Radical Biology and …, 2007 - Elsevier
Oxidative stress has been implicated to play a crucial role in the pathogenesis of a number
of diseases, including neurodegenerative disorders, cancer, and ischemia, just to name a …
of diseases, including neurodegenerative disorders, cancer, and ischemia, just to name a …
New insights into an old protein: the functional diversity of mammalian glyceraldehyde-3-phosphate dehydrogenase
MA Sirover - Biochimica et Biophysica Acta (BBA)-Protein Structure …, 1999 - Elsevier
Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) was considered a classical
glycolytic protein examined for its pivotal role in energy production. It was also used as a …
glycolytic protein examined for its pivotal role in energy production. It was also used as a …
Glyceraldehyde-3-phosphate dehydrogenase, apoptosis, and neurodegenerative diseases
DM Chuang, C Hough… - Annu. Rev. Pharmacol …, 2005 - annualreviews.org
▪ Abstract Increasing evidence supports the notion that glyceraldehyde-3-phosphate
dehydrogenase (GAPDH) is a protein with multiple functions, including its surprising role in …
dehydrogenase (GAPDH) is a protein with multiple functions, including its surprising role in …
Excitotoxic neuronal death and the pathogenesis of Huntington's disease
Huntington's disease (HD) is a neurodegenerative hereditary illness originated by the
mutation of the gene encoding the huntingtin-protein (htt). Mutated htt (mhtt) is characterized …
mutation of the gene encoding the huntingtin-protein (htt). Mutated htt (mhtt) is characterized …
Neurotoxicity of advanced glycation end-products for cultured cortical neurons
M Takeuchi, R Bucala, T Suzuki… - … of Neuropathology & …, 2000 - academic.oup.com
The Maillard reaction that leads to the formation of advanced glycation end-products (AGEs)
plays an important role in the pathogenesis of angiopathy in diabetic patients and in aging …
plays an important role in the pathogenesis of angiopathy in diabetic patients and in aging …
[HTML][HTML] GAPDH as a sensor of NO stress
MR Hara, MB Cascio, A Sawa - … et Biophysica Acta (BBA)-Molecular Basis …, 2006 - Elsevier
Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) is a classic glycolytic enzyme, and
accumulating evidence has suggested that GAPDH is a multi-functional protein. In particular …
accumulating evidence has suggested that GAPDH is a multi-functional protein. In particular …
The triangle of death in Alzheimer's disease brain: the aberrant cross-talk among energy metabolism, mammalian target of rapamycin signaling, and protein …
Significance: Alzheimer's disease (AD) is a multifactorial neurodegenerative disorder and
represents one of the most disabling conditions. AD shares many features in common with …
represents one of the most disabling conditions. AD shares many features in common with …