Aryl hydrocarbon receptor (AHR) was initially discovered as a cellular protein involved in
mediating the detoxification of xenobiotic compounds. Extensive research in the past two …

The Vav family is a group of tyrosine phosphorylation-regulated signal transduction
molecules hierarchically located downstream of protein tyrosine kinases. The main function …

Hepatic nerves have a complex role in synchronizing liver metabolism. Here, we used three-
dimensional (3D) immunoimaging to explore the integrity of the hepatic nervous system in …

Arterial hypertension is a common health problem that affects 25% of the adult population in
industrialized societies, and is a major risk factor for myocardial infarction and stroke …

Vav proteins are guanine nucleotide exchange factors (GEFs) for Rho family GTPases. They
control processes including T cell activation, phagocytosis, and migration of normal and …

Vav proteins play roles as guanosine nucleotide exchange factors for Rho GTPases and
signaling adaptors downstream of protein tyrosine kinases. The recent sequencing of the …

Fungal infections are major causes of morbidity and mortality, especially in
immunocompromised individuals. The innate immune system senses fungal pathogens …

Germline activation of H-RAS oncogenes is the primary cause of Costello syndrome (CS), a
neuro-cardio-facio-cutaneous developmental syndrome. Here we describe the generation of …

Chicken is a major source of protein for the increasing human population and is useful for
research purposes. There are almost 1,600 distinct regional breeds of chicken across the …

Proper regulation of arterial blood pressure is essential to allow permanent adjustment of
nutrient and oxygen supply to organs and tissues according to their need. This is achieved …