Challenges and opportunities in bioimage analysis

X Li, Y Zhang, J Wu, Q Dai - Nature methods, 2023 - nature.com
Advanced imaging techniques provide holistic observations of complicated biological
phenomena across multiple scales while posing great challenges to data analysis. We …

[HTML][HTML] Live-cell imaging in the deep learning era

JW Pylvänäinen, E Gómez-de-Mariscal… - Current Opinion in Cell …, 2023 - Elsevier
Live imaging is a powerful tool, enabling scientists to observe living organisms in real time.
In particular, when combined with fluorescence microscopy, live imaging allows the …

Light-sheets and smart microscopy, an exciting future is dawning

S Daetwyler, RP Fiolka - Communications biology, 2023 - nature.com
Light-sheet fluorescence microscopy has transformed our ability to visualize and
quantitatively measure biological processes rapidly and over long time periods. In this …

Three-dimensional structured illumination microscopy with enhanced axial resolution

X Li, Y Wu, Y Su, I Rey-Suarez, C Matthaeus… - Nature …, 2023 - nature.com
The axial resolution of three-dimensional structured illumination microscopy (3D SIM) is
limited to∼ 300 nm. Here we present two distinct, complementary methods to improve axial …

Virtual-scanning light-field microscopy for robust snapshot high-resolution volumetric imaging

Z Lu, Y Liu, M Jin, X Luo, H Yue, Z Wang, S Zuo… - Nature …, 2023 - nature.com
Abstract High-speed three-dimensional (3D) intravital imaging in animals is useful for
studying transient subcellular interactions and functions in health and disease. Light-field …

Live-cell imaging powered by computation

H Shroff, I Testa, F Jug, S Manley - Nature Reviews Molecular Cell …, 2024 - nature.com
The proliferation of microscopy methods for live-cell imaging offers many new possibilities
for users but can also be challenging to navigate. The prevailing challenge in live-cell …

Stimulated emission depletion microscopy

G Lukinavičius, J Alvelid, R Gerasimaitė… - Nature Reviews …, 2024 - nature.com
In this Primer, we focus on the most recent advancements in stimulated emission depletion
(STED) microscopy, encompassing optics, computational microscopy and probes design …

Image processing tools for petabyte-scale light sheet microscopy data

X Ruan, M Mueller, G Liu, F Görlitz, TM Fu, DE Milkie… - Nature …, 2024 - nature.com
Light sheet microscopy is a powerful technique for high-speed three-dimensional imaging of
subcellular dynamics and large biological specimens. However, it often generates datasets …

A systematic review of deep learning-based cervical cytology screening: from cell identification to whole slide image analysis

P Jiang, X Li, H Shen, Y Chen, L Wang, H Chen… - Artificial Intelligence …, 2023 - Springer
Cervical cancer is one of the most common cancers in daily life. Early detection and
diagnosis can effectively help facilitate subsequent clinical treatment and management. With …

[HTML][HTML] Detection of various gastrointestinal tract diseases through a deep learning method with ensemble ELM and explainable AI

MF Ahamed, M Nahiduzzaman, MR Islam… - Expert Systems with …, 2024 - Elsevier
The rising prevalence of gastrointestinal (GI) tract disorders worldwide highlights the urgent
need for precise diagnosis, as these diseases greatly affect human life and contribute to …