An update on the mechanisms related to cell death and toxicity of doxorubicin and the protective role of nutrients

A Varela-López, M Battino, MD Navarro-Hortal… - Food and Chemical …, 2019 - Elsevier
Doxorubicin (DOX), is a very effective chemotherapeutic agent against cancer whose clinical
use is limited by toxicity. Different strategies have been proposed to attenuate toxicity …

Emerging chitosan grafted essential oil components: A review on synthesis, characterization, and potential application

X Ding, L Zhao, IM Khan, L Yue, Y Zhang… - Carbohydrate Polymers, 2022 - Elsevier
Chitosan is a green, low-cost natural polymer material. The bioactivity of chitosan can be
enhanced by coupling with essential oil chemicals, which can broaden the range of …

Lapatinib induces mitochondrial dysfunction to enhance oxidative stress and ferroptosis in doxorubicin-induced cardiomyocytes via inhibition of PI3K/AKT signaling …

L Sun, H Wang, D Xu, S Yu, L Zhang, X Li - Bioengineered, 2022 - Taylor & Francis
Lapatinib (LAP) is an important anti-cancer drug and is frequently alongside doxorubicin
(DOX) as a combination therapy for better anti-cancer efficacy. However, many studies have …

A review of the pharmacological characteristics of vanillic acid

A Ingole, MP Kadam, AP Dalu, SM Kute… - Journal of Drug …, 2021 - jddtonline.info
A dihydroxybenzoic acid analog used as a flavoring agent is vanillic acid (4hydroxy-3-
methoxybenzoic acid). It's a form of vanillin that has been oxidized. It's also a step in the …

Cardioprotective potential of vanillic acid

B Yalameha, HR Nejabati… - Clinical and Experimental …, 2023 - Wiley Online Library
Nowadays, cardiovascular diseases (CVDs) are a global threat to public health, accounting
for almost one‐third of all deaths worldwide. One of the key mechanistic pathways …

Vanillic acid alleviates methamphetamine-induced mitochondrial toxicity in cardiac mitochondria via antioxidant activity and inhibition of MPT Pore opening: an in-vitro …

M Shabani, Z Jamali, D Bayrami, A Salimi - BMC Pharmacology and …, 2023 - Springer
Background Methamphetamine is widely abused in all parts of the world. It has been
reported that short-term and long-term methamphetamine exposure could damage the …

Factors affecting consumer purchasing behavior of functional food: a comparative analysis for consumer management

FP Salvatore, N Adamashvili, F Conto - British Food Journal, 2022 - emerald.com
Purpose The main aims are underlining the role of functional foods (FFs) for population
wellbeing, investigating the reasons in the self-consciousness of the different countries' …

Unveiling the effect of molecular weight of vanillic acid grafted chitosan hydrogel films on physical, antioxidant, and antimicrobial properties for application in food …

B Bakar, SS Pekdemir, E Birhanlı, A Ulu… - International Journal of …, 2024 - Elsevier
Till now, a wide range of chitosan (CHS)-based food packaging films have been developed.
Yet, the role of molecular weight (MW), which is an important physical property of CHS, in …

[HTML][HTML] Docosahexaenoic acid protects against palmitate-induced mitochondrial dysfunction in diabetic cardiomyopathy

T Gui, Y Li, S Zhang, N Zhang, Y Sun, F Liu… - Biomedicine & …, 2020 - Elsevier
Objective Regular consumption of n-3 polyunsaturated fatty acids is associated with
decreased cardiovascular morbidity and mortality. This study assessed the therapeutic effect …

Role of nutrients and foods in attenuation of cardiac remodeling through oxidative stress pathways

T Lazzarin, LR Garcia, D Martins, DAR Queiroz… - Antioxidants, 2022 - mdpi.com
Cardiac remodeling is defined as a group of molecular, cellular, and interstitial changes that
manifest clinically as changes in the heart's size, mass, geometry, and function after different …