The advent of iPSCs has brought about a significant transformation in stem cell research,
opening up promising avenues for advancing cancer treatment. The formation of cancer is a …

Introduction Gliomas, especially the glioblastomas, are one of the most aggressive
intracranial tumors with poor prognosis. This might be explained by the heterogeneity of …

Simple Summary Glioblastoma is a highly aggressive brain cancer, and early detection and
accurate diagnosis are crucial for effective treatment. Traditional diagnostic methods have …

Simple Summary Recent research has revealed the involvement of long non-coding RNAs
(lncRNAs) and micro RNAs (miRNAs) in glioma development and advancement, suggesting …

Targeted molecular therapy, for example, with sorafenib (SF) is considered as a new and
potent strategy for glioblastoma (GBM) that remains hard to treat today. Several clinical trials …

Glioblastoma (GBM) has a poor prognosis due to its aggressive growth and resistance to
postoperative treatments. The hypoxic microenvironment plays a significant role in tumor …

The rapid advancement of nanotechnology in recent years has opened new avenues of
investigation for biomedical sciences. Viral nanoparticles (VNPs) are formulated from plant …

Introduction Glioblastoma multiforme (GBM) is the deadliest type of brain cancer with poor
response to the available therapies, mainly due to intrinsic resistance mechanisms …

Glioblastoma (GBM) spheroids present as a promising alternative testing platform for in vivo
models of brain cancer, aiming at the 3Rs principle of animal use in pre-clinical trials …

Purpose Glioblastoma (GBM) has a poor prognosis after standard treatment. Recently,
metformin has been shown to have an antitumor effect on glioma cells. We performed the …