Toxoplasma gondii infection and its implications within the central nervous system

SK Matta, N Rinkenberger, IR Dunay… - Nature Reviews …, 2021 - nature.com
Toxoplasma gondii is a parasite that infects a wide range of animals and causes zoonotic
infections in humans. Although it normally only results in mild illness in healthy individuals …

HIV-related cerebral toxoplasmosis revisited: current concepts and controversies of an old disease

JE Vidal - Journal of the International Association of …, 2019 - journals.sagepub.com
Cerebral toxoplasmosis is the most common cause of expansive brain lesions in people
living with HIV/AIDS (PLWHA) and continues to cause high morbidity and mortality. The most …

Comprehensive Overview of Toxoplasma gondii-Induced and Associated Diseases

D Daher, A Shaghlil, E Sobh, M Hamie, ME Hassan… - Pathogens, 2021 - mdpi.com
Toxoplasma gondii (T. gondii) is a prevalent protozoan parasite of medical and veterinary
significance. It is the etiologic agent of toxoplasmosis, a neglected disease in which …

Pathogenesis of ocular toxoplasmosis

JR Smith, LM Ashander, SL Arruda, CA Cordeiro… - Progress in Retinal and …, 2021 - Elsevier
Ocular toxoplasmosis is a retinitis–almost always accompanied by vitritis and choroiditis–
caused by intraocular infection with Toxoplasma gondii. Depending on retinal location, this …

Influence of the Host and Parasite Strain on the Immune Response During Toxoplasma Infection

D Mukhopadhyay, D Arranz-Solís… - Frontiers in Cellular and …, 2020 - frontiersin.org
Toxoplasma gondii is an exceptionally successful parasite that infects a very broad host
range, including humans, across the globe. The outcome of infection differs remarkably …

Cerebral toxoplasmosis in HIV-infected patients: a review

S Dian, AR Ganiem, S Ekawardhani - Pathogens and global health, 2023 - Taylor & Francis
Toxoplasma gondii infection in the central nervous system commonly occurs among
immunodeficient patients. Its prevalence is high in countries with a high burden of HIV and …

[HTML][HTML] Toxoplasmosis in Germany: epidemiology, diagnosis, risk factors, and treatment

U Pleyer, U Gross, D Schlüter, H Wilking… - Deutsches Ärzteblatt …, 2019 - ncbi.nlm.nih.gov
Background With approximately 30% of the world population infected, Toxoplasma gondii is
one of the most widespread pathogenic parasites in both humans and animals and a major …

[HTML][HTML] Early passage of Toxoplasma gondii across the blood–brain barrier

EC Ross, GC Olivera, A Barragan - Trends in parasitology, 2022 - cell.com
The blood–brain barrier (BBB) efficiently protects the central nervous system (CNS) from
infectious insults. Yet, the apicomplexan parasite Toxoplasma gondii has a remarkable …

Toxoplasmosis: Current and emerging parasite druggable targets

RE Hajj, L Tawk, S Itani, M Hamie, J Ezzeddine… - Microorganisms, 2021 - mdpi.com
Toxoplasmosis is a prevalent disease affecting a wide range of hosts including
approximately one-third of the human population. It is caused by the sporozoan parasite …

[HTML][HTML] The Toxoplasma effector GRA28 promotes parasite dissemination by inducing dendritic cell-like migratory properties in infected macrophages

AL Ten Hoeve, L Braun, ME Rodriguez, GC Olivera… - Cell host & …, 2022 - cell.com
Upon pathogen detection, macrophages normally stay sessile in tissues while dendritic cells
(DCs) migrate to secondary lymphoid tissues. The obligate intracellular protozoan …