Mast cells are found resident in tissues throughout the body, particularly in association with
structures such as blood vessels and nerves, and in proximity to surfaces that interface the …

The macrophage (M phi) lineage is more complex than other myeloid lineages of
hematopoietic cells and includes strikingly different end cells such as Kupffer cells, alveolar …

Normal hematopoietic stem cells proliferate and differentiate in the presence of growth
factors such as interleukin-3 (IL-3). Transformation can alter their growth factor requirements …

Currently available evidence suggests that in the steady state, the majority of hematopoietic
stem cells are dormant in cell cycle and reside in the so-called G 0 period. Studies in our …

Biological Properties of IL-3 The hematopoietic lineages are derived from a common
pluripotential stem cell that gives rise to cells of both the myeloid and lymphoid lineages [11 …

We have used a serum-free culture system for enriched human hemopoietic progenitors to
analyze the developmental stages and lineage specificities of the human hemopoietic …

Fig 1. Distal tip cells (dtc) in the developing gonad of C. elegans produce a factor that
prevents cells in the shaded area from entering meiosis. The anchor cell (ac) produces a …

The genetic sequences encoding the gibbon and human interleukin 3 (IL 3) proteins were
molecularly cloned. The amino acid sequence of the mature gibbon IL 3 protein proved to …

The development and differentiation of macrophages in the fetal mouse yolk sac were
studied morphologically in four different culture experiments. In the culture of mouse …

Serial observations of blast cell colony development from spleen cells of mice treated with 5-
fluorouracil (5-FU) four days earlier revealed that either form of human interleukin-1 (IL-1 …