Coiled coils: attractive protein folding motifs for the fabrication of self-assembled, responsive and bioactive materials
The coiled coil is a superhelical protein structural motif that consists of two or more α-helical
peptides that are wrapped around each other in superhelical fashion. Coiled coils are …
peptides that are wrapped around each other in superhelical fashion. Coiled coils are …
Biomaterials via peptide assembly: Design, characterization, and application in tissue engineering
A core challenge in biomaterials, with both fundamental significance and technological
relevance, concerns the rational design of bioactive microenvironments. Designed properly …
relevance, concerns the rational design of bioactive microenvironments. Designed properly …
The centrosome is a selective condensate that nucleates microtubules by concentrating tubulin
Centrosomes are non-membrane-bound compartments that nucleate microtubule arrays.
They consist of nanometer-scale centrioles surrounded by a micron-scale, dynamic …
They consist of nanometer-scale centrioles surrounded by a micron-scale, dynamic …
Bacterial nanobioreactors–directing enzyme packaging into bacterial outer membrane vesicles
All bacteria shed outer membrane vesicles (OMVs) loaded with a diverse array of small
molecules, proteins, and genetic cargo. In this study we sought to hijack the bacterial cell …
molecules, proteins, and genetic cargo. In this study we sought to hijack the bacterial cell …
Peptide-PAINT super-resolution imaging using transient coiled coil interactions
Super-resolution microscopy is transforming research in the life sciences by enabling the
visualization of structures and interactions on the nanoscale. DNA-PAINT is a relatively easy …
visualization of structures and interactions on the nanoscale. DNA-PAINT is a relatively easy …
Covalent diabodies and uses thereof
LS Johnson, L Huang - US Patent 9,284,375, 2016 - Google Patents
C07K16/283—Immunoglobulins [IGs], eg monoclonal or polyclonal antibodies against
material from animals or humans against receptors, cell surface antigens or cell surface …
material from animals or humans against receptors, cell surface antigens or cell surface …
De novo design of orthogonal peptide pairs forming parallel coiled‐coil heterodimers
H Gradišar, R Jerala - Journal of Peptide Science, 2011 - Wiley Online Library
We used the principles governing the selectivity and stability of coiled‐coil segments to
design and experimentally test a set of four pairs of parallel coiled‐coil‐forming peptides …
design and experimentally test a set of four pairs of parallel coiled‐coil‐forming peptides …
A near-infrared BiFC reporter for in vivo imaging of protein-protein interactions
GS Filonov, VV Verkhusha - Chemistry & biology, 2013 - cell.com
Studies of protein-protein interactions deep in organs and in whole mammals have been
hindered by a lack of genetically encoded fluorescent probes in near-infrared region for …
hindered by a lack of genetically encoded fluorescent probes in near-infrared region for …
Immobilization of growth factors for cell therapy manufacturing
D Enriquez-Ochoa, P Robles-Ovalle… - … in bioengineering and …, 2020 - frontiersin.org
Cell therapy products exhibit great therapeutic potential but come with a deterring price tag
partly caused by their costly manufacturing processes. The development of strategies that …
partly caused by their costly manufacturing processes. The development of strategies that …
Molecular mechanics of coiled coils loaded in the shear geometry
Coiled coils are important nanomechanical building blocks in biological and biomimetic
materials. A mechanistic molecular understanding of their structural response to mechanical …
materials. A mechanistic molecular understanding of their structural response to mechanical …