The functions of metamorphic metallothioneins in zinc and copper metabolism
Recent discoveries in zinc biology provide a new platform for discussing the primary
physiological functions of mammalian metallothioneins (MTs) and their exquisite zinc …
physiological functions of mammalian metallothioneins (MTs) and their exquisite zinc …
Metals in neurobiology: probing their chemistry and biology with molecular imaging
The brain is a singular organ of unique biological complexity that serves as the command
center for cognitive and motor function. As such, this specialized system also possesses a …
center for cognitive and motor function. As such, this specialized system also possesses a …
Metallothioneins: unparalleled diversity in structures and functions for metal ion homeostasis and more
CA Blindauer, OI Leszczyszyn - Natural product reports, 2010 - pubs.rsc.org
Covering: 1999 to 2009 Metallothioneins have been the subject of intense study for five
decades, and have greatly inspired the development of bio-analytical methodologies …
decades, and have greatly inspired the development of bio-analytical methodologies …
Metallothionein functions and structural characteristics
E Carpene, G Andreani, G Isani - Journal of trace elements in medicine and …, 2007 - Elsevier
Metallothioneins (MTs) are low molecular weight proteins characterized by a high cysteine
content and give rise to metal-thiolate clusters. Most MTs have two metal clusters containing …
content and give rise to metal-thiolate clusters. Most MTs have two metal clusters containing …
The metallothionein/thionein system: an oxidoreductive metabolic zinc link
SG Bell, BL Vallee - Chembiochem, 2009 - Wiley Online Library
Metallothioneins (MTs) were discovered more than 50 years ago and identified as low‐
molecular weight, sulfhydryl‐rich proteins that were subsequently found to bind zinc …
molecular weight, sulfhydryl‐rich proteins that were subsequently found to bind zinc …
Advances in the molecular understanding of biological zinc transport
CA Blindauer - Chemical Communications, 2015 - pubs.rsc.org
Between 5 and 10% of all proteins of a given organism are estimated to require zinc for
function, and hence zinc is essential for almost any given metabolic process. It is therefore of …
function, and hence zinc is essential for almost any given metabolic process. It is therefore of …
Metal binding and interdomain thermodynamics of mammalian metallothionein-3: enthalpically favoured Cu+ supplants entropically favoured Zn 2+ to form Cu 4+ …
MR Mehlenbacher, R Elsiesy, R Lakha… - Chemical …, 2022 - pubs.rsc.org
Metallothioneins (MTs) are a ubiquitous class of small metal-binding proteins involved in
metal homeostasis and detoxification. While known for their high affinity for d10 metal ions …
metal homeostasis and detoxification. While known for their high affinity for d10 metal ions …
Metallothionein polymorphisms in pathological processes
Metallothioneins (MTs) are a class of metal-binding proteins characterized by a high
cysteine content and low molecular weight. MTs play an important role in metal metabolism …
cysteine content and low molecular weight. MTs play an important role in metal metabolism …
Metallothioneins induction and antioxidative response in aquatic worms Tubifex tubifex (Oligochaeta, Tubificidae) exposed to copper
YY Mosleh, S Paris-Palacios, S Biagianti-Risbourg - Chemosphere, 2006 - Elsevier
Metallothioneins (MTs), are low molecular weight proteins, mainly implicated in metal ion
detoxification. Increase in MT contents is considered as a specific biomarker of metal …
detoxification. Increase in MT contents is considered as a specific biomarker of metal …
Metal-induced conformational changes of human metallothionein-2A: a combined theoretical and experimental study of metal-free and partially metalated …
Electrospray ionization ion mobility mass spectrometry (ESI IM-MS) and molecular dynamics
(MD) simulations reveal new insights into metal-induced conformational changes and the …
(MD) simulations reveal new insights into metal-induced conformational changes and the …