Beyond THC and endocannabinoids

P Pacher, NM Kogan… - Annual review of …, 2020 - annualreviews.org
Research in the cannabinoid field, namely on phytocannabinoids, the endogenous
cannabinoids anandamide and 2-arachidonoyl glycerol and their metabolizing and synthetic …

Cannabidiol as a novel candidate alcohol use disorder pharmacotherapy: a systematic review

J Turna, SK Syan, BN Frey, B Rush… - Alcoholism: Clinical …, 2019 - Wiley Online Library
There is substantial interest in the therapeutic potential of cannabidiol (CBD), a
nonpsychoactive cannabinoid found in plants of the genus Cannabis. The goal of the current …

Cannabidiol attenuates alcohol-induced liver steatosis, metabolic dysregulation, inflammation and neutrophil-mediated injury

Y Wang, P Mukhopadhyay, Z Cao, H Wang, D Feng… - Scientific reports, 2017 - nature.com
Cannabidiol (CBD) is a non-psychoactive component of marijuana, which has anti-
inflammatory effects. It has also been approved by FDA for various orphan diseases for …

[HTML][HTML] Safety assessment of a hemp extract using genotoxicity and oral repeat-dose toxicity studies in Sprague-Dawley rats

M Dziwenka, R Coppock, MC Alexander, E Palumbo… - Toxicology reports, 2020 - Elsevier
Cannabinoids are extracted from Cannabis sativa L. and are used for a variety of medicinal
purposes. Recently, there has been a focus on the cannabinoid Cannabidiol (CBD) and its …

The Role of Cannabidiol in Liver Disease: A Systemic Review

S Chen, JK Kim - International Journal of Molecular Sciences, 2024 - mdpi.com
Cannabidiol (CBD), a non-psychoactive phytocannabinoid abundant in Cannabis sativa,
has gained considerable attention for its anti-inflammatory, antioxidant, analgesic, and …

Protective effect of dendropanoxide against cadmium-induced hepatotoxicity via anti-inflammatory activities in Sprague-Dawley rats

S Gali, S Sharma, A Kundu, E Lee, JH Han… - Toxicology …, 2023 - Taylor & Francis
Cadmium (Cd) accumulates in the body through contaminated foods or water and causes
pathological damage to the liver via oxidative stress and inflammatory reactions. This study …

Cannabis in liver disorders: a friend or a foe?

H Goyal, MR Rahman, A Perisetti, N Shah… - European journal of …, 2018 - journals.lww.com
The recent legalization of recreational marijuana use in some parts of the world, the
discovery of new indications for the clinical application of cannabis, and the acceptance of …

Cannabidiol rescues acute hepatic toxicity and seizure induced by cocaine

LR Vilela, LF Gomides, BA David… - Mediators of …, 2015 - Wiley Online Library
Cocaine is a commonly abused illicit drug that causes significant morbidity and mortality.
The most severe and common complications are seizures, ischemic strokes, myocardial …

Evaluation of hepatorenal impairments in Wistar rats coexposed to low-dose lead, cadmium and manganese: insights into oxidative stress mechanism

OO Oladipo, JO Ayo, SF Ambali… - Toxicology mechanisms …, 2016 - Taylor & Francis
The study aims to evaluate effects of chronic low-dose coexposure to lead (Pb), cadmium
(Cd) and manganese (Mn) on hepatorenal toxicity and oxidative stress. Young male Wistar …

Modulatory effects of methanol extract of Artocarpus altilis (Moraceae) on cadmium-induced hepatic and renal toxicity in male Wistar rats

OA Adaramoye, OO Akanni - Pathophysiology, 2016 - Elsevier
Abstract Background Cadmium (Cd) is an environmental risk factor with an established
toxicity in animals. Therefore, natural antioxidants may be protective against Cd-toxicity. The …