By 2050, the American 85 years old and over population will triple. Clinicians and the public
health community need to develop a culture of sensitivity to the needs of this population and …

Polypharmacy is very common in older adults and increases the risk of inappropriate and
unsafe prescribing for older adults. Older adults, particularly women (who make up the …

Objective Polypharmacy is the concomitant use of several drugs by a single person, and it
increases the risk of adverse drug-related events in older adults. Little is known about the …

Aims Deprescribing is a suggested intervention to reverse the potential iatrogenic harms of
inappropriate polypharmacy. The review aimed to determine whether or not deprescribing is …

The Blood Cholesterol Expert Panel (Expert Panel) was originally convened as the Expert
Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (Adult …

The International Conference on Harmonization considers older people a 'special
population', as they differ from younger adults in terms of comorbidity, polypharmacy …

Caring for older adults with multiple chronic conditions (MCCs) is challenging. The American
Geriatrics Society (AGS) previously developed The AGS Guiding Principles for the Care of …

Importance For patients with limited prognosis, some medication risks may outweigh the
benefits, particularly when benefits take years to accrue; statins are one example. Data are …

Abstract Purpose of Review Hypoglycemia is the most common and often treatment-limiting
serious adverse effect of diabetes therapy. Despite being potentially preventable …

Context To better target services to those who may benefit, many guidelines recommend
incorporating life expectancy into clinical decisions. Objective To assess the quality and …