Breast cancer is the most prevalent cancer in the world. Currently, the main treatments for
breast cancer are radiotherapy, chemotherapy, targeted therapy and surgery. The treatment …

Breast cancer has become a leading cause of cancer-related deaths in women worldwide.
DNA methylation has been revealed to play an enormously important role in the …

Anesthetics are extensively used during cancer surgeries. The progression of cancer can be
influenced by perioperative events such as exposure to general or local anesthesia …

Sickle cell disease (SCD) is one of the most common inherited hemoglobinopathy disorders
that affects millions of people worldwide. Reactivation of HBG (HBG1, HBG2) gene …

Disruption in DNA methylation processes can lead to alteration in gene expression and
function that would ultimately result in malignant transformation. In this way, studies have …

It is well established that transcriptional silencing of critical tumor suppressor genes by DNA
methylation is a fundamental process in the initiation of lung cancer. However, the …

Organic compounds have been linked to adverse pregnancy complications.
Perfluorooctanesulfonic acid (PFOS), a man-made fluorosurfactant and global pollutant, has …

Several humans' diseases such as; cancer, heart disease, diabetes retain an etiology of
epigenetic, and a new therapeutic option termed as “epigenetic therapy” can offer a potential …

Purpose: To explore alterations in gene promoter methylation as a potential cause of
acquired drug resistance to doxorubicin or combined treatment with 5-fluorouracil and …

Type 2 diabetes mellitus (T2DM) steadily increases in prevalence since the 1950's, the
period of widespread distribution of refrigerated pasteurized cow's milk. Whereas …