Synthetic cells in biomedical applications

W Sato, T Zajkowski, F Moser… - Wiley Interdisciplinary …, 2022 - Wiley Online Library
Synthetic cells are engineered vesicles that can mimic one or more salient features of life.
These features include directed localization, sense‐and‐respond behavior, gene …

Cell-free biosensors for biomedical applications

PL Voyvodic, J Bonnet - Current opinion in biomedical engineering, 2020 - Elsevier
Recent years have witnessed a rapid increase of the use of cell-free systems for biosensor
engineering. Building on the past decade of synthetic biology research mostly performed in …

Metabolic perceptrons for neural computing in biological systems

A Pandi, M Koch, PL Voyvodic, P Soudier… - Nature …, 2019 - nature.com
Synthetic biological circuits are promising tools for developing sophisticated systems for
medical, industrial, and environmental applications. So far, circuit implementations …

Computational capabilities of a multicellular reservoir computing system

V Nikolić, M Echlin, B Aguilar, I Shmulevich - Plos one, 2023 - journals.plos.org
The capacity of cells to process information is currently used to design cell-based tools for
ecological, industrial, and biomedical applications such as detecting dangerous chemicals …

Compiling elementary mathematical functions into finite chemical reaction networks via a polynomialization algorithm for ODEs

M Hemery, F Fages, S Soliman - … September 22–24, 2021, Proceedings 19, 2021 - Springer
The Turing completeness result for continuous chemical reaction networks (CRN) shows
that any computable function over the real numbers can be computed by a CRN over a finite …

Advances in single cell technologies in immunology

JR Choi - Biotechniques, 2020 - Taylor & Francis
The immune system is composed of heterogeneous populations of immune cells that
regulate physiological processes and protect organisms against diseases. Single cell …

Algebraic biochemistry: a framework for analog online computation in cells

M Hemery, F Fages - … Conference on Computational Methods in Systems …, 2022 - Springer
The Turing completeness of continuous chemical reaction networks (CRNs) states that any
computable real function can be computed by a continuous CRN on a finite set of molecular …

On a model of online analog computation in the cell with absolute functional robustness: algebraic characterization, function compiler and error control

M Hemery, F Fages - Theoretical Computer Science, 2024 - Elsevier
The Turing completeness of continuous Chemical Reaction Networks (CRNs) states that any
computable real function can be computed by a continuous CRN on a finite set of molecular …

On robustness computation and optimization in BIOCHAM-4

F Fages, S Soliman - Computational Methods in Systems Biology: 16th …, 2018 - Springer
BIOCHAM-4 is a tool for modeling, analyzing and synthesizing biochemical reaction
networks with respect to some formal, yet possibly imprecise, specification of their behavior …

Qualitative modeling, analysis and control of synthetic regulatory circuits

M Chaves, H De Jong - Synthetic Gene Circuits: Methods and Protocols, 2021 - Springer
Qualitative modeling approaches are promising and still underexploited tools for the
analysis and design of synthetic circuits. They can make predictions of circuit behavior in the …