An overview of the optical and electrochemical methods for detection of DNA-drug interactions
M Aleksić, V Kapetanović - Acta Chimica Slovenica, 2014 - farfar.pharmacy.bg.ac.rs
A large number of inorganic and organic compounds is able to bind to DNA and form
complexes. Among them, drugs are very important, especially chemotherapeutics. This …
complexes. Among them, drugs are very important, especially chemotherapeutics. This …
Gold nanoparticles and reduced graphene oxide‐gold nanoparticle composite materials as covalent drug delivery systems for breast cancer treatment
AuNPs and AuNPs/RGO composites were engineered as drug delivery nanoplatforms to
efficiently deliver the anti‐cancer drug to MCF‐7 breast cancer cells. The anti‐cancer drug …
efficiently deliver the anti‐cancer drug to MCF‐7 breast cancer cells. The anti‐cancer drug …
Electrochemical and spectroscopic studies of the interaction of antiviral drug Tenofovir with single and double stranded DNA
K Morawska, T Popławski, W Ciesielski… - …, 2018 - Elsevier
In the present study, the electrochemical behavior of the antiviral drug tenofovir (tnf) on a
boron-doped diamond electrode (BDDE) has been studied using square-wave voltammetry …
boron-doped diamond electrode (BDDE) has been studied using square-wave voltammetry …
Interaction of mitoxantrone with abasic sites-DNA strand cleavage and inhibition of apurinic/apyrimidinic endonuclease 1, APE1
IG Minko, SA Moellmer, MM Luzadder, R Tomar… - DNA repair, 2024 - Elsevier
Abstract Mitoxantrone (1, 4-dihydroxy-5, 8-bis [2-(2-hydroxyethylamino) ethylamino]-
anthracene-9, 10-dione) is a clinically-relevant synthetic anthracenedione that functions as a …
anthracene-9, 10-dione) is a clinically-relevant synthetic anthracenedione that functions as a …
Synthesis and evaluation of new antitumor 3-aminomethyl-4, 11-dihydroxynaphtho [2, 3-f] indole-5, 10-diones
AE Shchekotikhin, VA Glazunova… - European Journal of …, 2014 - Elsevier
A series of new 3-aminomethyl-4, 11-dihydroxynaphtho [2, 3-f] indole-5, 10-diones 6–13
bearing the cyclic diamine in the position 3 of the indole ring was synthesized. The majority …
bearing the cyclic diamine in the position 3 of the indole ring was synthesized. The majority …
[HTML][HTML] A 4: 1 stoichiometric binding and stabilization of mitoxantrone-parallel stranded G-quadruplex complex established by spectroscopy techniques
TP Pradeep, R Barthwal - Journal of Photochemistry and Photobiology B …, 2016 - Elsevier
Small molecule ligands which specifically bind and stabilize G-quadruplex structures in
telomeric ends inhibit the activity of telomerase enzyme, an important marker for cancer …
telomeric ends inhibit the activity of telomerase enzyme, an important marker for cancer …
Unveiling the multifaceted interactions of antitumor drug mitoxantrone with ct-DNA through biophysical and in silico studies
CH Pasangha, N Kishore - International Journal of Biological …, 2024 - Elsevier
Mitoxantrone, an anthraquinone derivative, is a widely used anticancer drug with its well-
known ability to engage in complex interactions with DNA. Although known for its …
known ability to engage in complex interactions with DNA. Although known for its …
[PDF][PDF] On the existence of the DNA resonance code and its possible mechanistic connection to the neural code
IV Savelyev, NV Zyryanova, OO Polesskaya… - …, 2019 - dnaresonance.org
ABSTRACT A possible role of DNA sequence-specific electromagnetic resonances in the
formation of the morphogenic field is discussed. It is proposed that the morphogenic field is …
formation of the morphogenic field is discussed. It is proposed that the morphogenic field is …
NMR based structure reveals groove binding of mitoxantrone to two sites of [d-(TTAGGGT)] 4 having human telomeric DNA sequence leading to thermal stabilization …
S Tripathi, R Barthwal - International journal of biological macromolecules, 2018 - Elsevier
Interaction of mitoxantrone (MTX) with G-quadruplex, leading to inhibition of telomerase
enzyme and anticancer action, is not understood. Titrations of MTX with [d-(TTAGGGT)] 4 …
enzyme and anticancer action, is not understood. Titrations of MTX with [d-(TTAGGGT)] 4 …
NMR structure of dual site binding of mitoxantrone dimer to opposite grooves of parallel stranded G-quadruplex [d-(TTGGGGT)] 4
TP Pradeep, R Barthwal - Biochimie, 2016 - Elsevier
The formation of complex between anti-cancer drug mitoxantrone (MTX) and tetra-molecular
parallel G-quadruplex DNA [d-(TTGGGGT)] 4 has been studied by solution state one and …
parallel G-quadruplex DNA [d-(TTGGGGT)] 4 has been studied by solution state one and …