[HTML][HTML] Diagnostic armamentarium of infectious keratitis: A comprehensive review

DSJ Ting, BP Gopal, R Deshmukh, GD Seitzman… - The Ocular Surface, 2022 - Elsevier
Infectious keratitis (IK) represents the leading cause of corneal blindness worldwide,
particularly in developing countries. A good outcome of IK is contingent upon timely and …

Next-generation antimicrobial susceptibility testing

A Van Belkum, WM Dunne Jr - Journal of clinical microbiology, 2013 - Am Soc Microbiol
Antimicrobial resistance has emerged as one of the most-significant health care problems of
the new millennium, and the clinical microbiology laboratory plays a central role in …

Nanoarray digital polymerase chain reaction with high-resolution melt for enabling broad bacteria identification and pheno–molecular antimicrobial susceptibility test

P Athamanolap, K Hsieh, CM O'Keefe… - Analytical …, 2019 - ACS Publications
Toward combating infectious diseases caused by pathogenic bacteria, there remains an
unmet need for diagnostic tools that can broadly identify the causative bacteria and …

[HTML][HTML] Rapid bacterial antibiotic susceptibility test based on simple surface-enhanced Raman spectroscopic biomarkers

CY Liu, YY Han, PH Shih, WN Lian, HH Wang… - Scientific reports, 2016 - nature.com
Rapid bacterial antibiotic susceptibility test (AST) and minimum inhibitory concentration
(MIC) measurement are important to help reduce the widespread misuse of antibiotics and …

[PDF][PDF] Rapid clinical bacteriology and its future impact

A Van Belkum, G Durand, M Peyret… - Annals of laboratory …, 2013 - synapse.koreamed.org
Clinical microbiology has always been a slowly evolving and conservative science. The sub-
field of bacteriology has been and still is dominated for over a century by culturebased …

Digital quantification of DNA replication and chromosome segregation enables determination of antimicrobial susceptibility after only 15 minutes of antibiotic exposure

NG Schoepp, EM Khorosheva… - Angewandte Chemie …, 2016 - Wiley Online Library
Rapid antimicrobial susceptibility testing (AST) would decrease misuse and overuse of
antibiotics. The “holy grail” of AST is a phenotype‐based test that can be performed within a …

Droplet‐Based Single‐Cell Measurements of 16S rRNA Enable Integrated Bacteria Identification and Pheno‐Molecular Antimicrobial Susceptibility Testing from …

AM Kaushik, K Hsieh, KE Mach, S Lewis… - Advanced …, 2021 - Wiley Online Library
Empiric broad‐spectrum antimicrobial treatments of urinary tract infections (UTIs) have
contributed to widespread antimicrobial resistance. Clinical adoption of evidence‐based …

Integrated bacterial identification and antimicrobial susceptibility testing using PCR and high-resolution melt

P Athamanolap, K Hsieh, L Chen, S Yang… - Analytical …, 2017 - ACS Publications
Accurate and timely diagnostics are critical for managing bacterial infections. The current
gold standard, culture-based diagnostics, can provide clinicians with comprehensive …

Emerging analytical techniques for rapid pathogen identification and susceptibility testing

DJ Shin, N Andini, K Hsieh, S Yang… - Annual review of …, 2019 - annualreviews.org
In the face of looming threats from multi-drug resistant microorganisms, there is a growing
need for technologies that will enable rapid identification and drug susceptibility profiling of …

Early diagnosis of resistant pathogens: how can it improve antimicrobial treatment?

S Bhattacharya - Virulence, 2013 - Taylor & Francis
Infections with organisms that are resistant to various anti-microbial agents pose a serious
challenge to effective management of infections. Resistance to antimicrobial agents, which …