Despite extensive global efforts in the fight against killer infectious diseases, they still cause
one in four deaths worldwide and are important causes of long-term functional disability …

To determine the burden of community-acquired pneumonia (CAP) affecting adults in North
America, a comprehensive literature review was conducted to examine the incidence …

We aim to study the association of hyperlipidemia and statin use with COVID-19 severity. We
analysed a retrospective cohort of 717 patients admitted to a tertiary centre in Singapore for …

Viral influenza is a seasonal infection associated with significant morbidity and mortality. In
the United States more than 35,000 deaths and 200,000 hospitalizations due to influenza …

Tuberculosis (TB), caused by Mycobacterium tuberculosis (Mtb), remains a leading cause of
morbidity and mortality in humans worldwide. Currently, the standard treatment for TB …

Influenza is a seasonal viral infection associated with significant morbidity and mortality. In
2009, a novel H1N1 influenza A virus emerged and has been classified as a pandemic. In …

Importance Observational studies have reported that statin use may be associated with
improved outcomes of various infections. Ventilator-associated pneumonia (VAP) is the most …

Rationale: Simvastatin inhibits inflammatory responses in vitro and in murine models of lung
inflammation in vivo. As simvastatin modulates a number of the underlying processes …

Background Published data on antiinflammatory and immunomodulatory effects of statins
suggest they may reduce mortality risks associated with an unchecked immune response to …

Background Emerging epidemiological evidence suggests that statin use may reduce the
risk of infections and infection-related complications. Our objective was to examine the …