Revisiting fibrosis in inflammatory bowel disease: the gut thickens

S D'Alessio, F Ungaro, D Noviello, S Lovisa… - Nature Reviews …, 2022 - nature.com
Intestinal fibrosis, which is usually the consequence of chronic inflammation, is a common
complication of inflammatory bowel disease (IBD), including Crohn's disease and ulcerative …

Assessment of Crohn's disease-associated small bowel strictures and fibrosis on cross-sectional imaging: a systematic review

D Bettenworth, A Bokemeyer, M Baker, R Mao… - Gut, 2019 - gut.bmj.com
Patients with Crohn's disease commonly develop ileal and less commonly colonic strictures,
containing various degrees of inflammation and fibrosis. While predominantly inflammatory …

Expert consensus on optimal acquisition and development of the International Bowel Ultrasound Segmental Activity Score [IBUS-SAS]: a reliability and inter-rater …

KL Novak, K Nylund, C Maaser… - Journal of Crohn's …, 2021 - academic.oup.com
Abstract Background and Aims Intestinal ultrasound [IUS] is an accurate, patient-centreed
monitoring tool that objectively evaluates Crohn's disease [CD] activity. However no current …

ECCO-ESGAR topical review on optimizing reporting for cross-sectional imaging in inflammatory bowel disease

T Kucharzik, J Tielbeek, D Carter… - Journal of Crohn's …, 2022 - academic.oup.com
Abstract Background and Aims The diagnosis and follow up of patients with inflammatory
bowel disease [IBD] requires cross-sectional imaging modalities, such as intestinal …

Defining transabdominal intestinal ultrasound treatment response and remission in inflammatory bowel disease: systematic review and expert consensus statement

JFKF Ilvemark, T Hansen, TM Goodsall… - Journal of Crohn's …, 2022 - academic.oup.com
Abstract Background and Aims No consensus exists on defining intestinal ultrasound
response, transmural healing, or transmural remission in inflammatory bowel disease, nor …

Novel mechanisms and clinical trial endpoints in intestinal fibrosis

J Wang, S Lin, JM Brown, D van Wagoner… - Immunological …, 2021 - Wiley Online Library
The incidence of inflammatory bowel diseases (IBD) worldwide has resulted in a global
public health challenge. Intestinal fibrosis leading to stricture formation and bowel …

[HTML][HTML] Early ultrasound response and progressive transmural remission after treatment with ustekinumab in Crohn's disease

T Kucharzik, R Wilkens, MA D'agostino… - Clinical …, 2023 - Elsevier
Background & Aims In this STARDUST substudy, the effect of ustekinumab on transmural
bowel inflammation was assessed in adults with moderate-to-severe Crohn's disease (CD) …

Reliability of CT enterography for describing fibrostenosing Crohn disease

F Rieder, C Ma, J Hanzel, JG Fletcher, ME Baker… - Radiology, 2024 - pubs.rsna.org
Background Standardized methods to measure and describe Crohn disease strictures at CT
enterography are needed to guide clinical decision making and for use in therapeutic …

Relevance of monitoring transmural disease activity in patients with Crohn's disease: current status and future perspectives

R Wilkens, KL Novak, C Maaser… - Therapeutic …, 2021 - journals.sagepub.com
Treatment targets of inflammatory bowel diseases (IBD), ulcerative colitis (UC) and Crohn's
disease (CD) have evolved over the last decade. Goals of therapy consisting of symptom …

Ultrasound elastography in inflammatory bowel diseases: a systematic review of accuracy compared with histopathological assessment

A Dal Buono, F Faita, L Peyrin-Biroulet… - Journal of Crohn's …, 2022 - academic.oup.com
Abstract Background and Aims Ultrasound elastography [USE] is an innovative, non-
invasive, promptly available, ancillary technique that has been proposed in the evaluation of …