Causal mapping of human brain function

SH Siddiqi, KP Kording, J Parvizi, MD Fox - Nature reviews …, 2022 - nature.com
Mapping human brain function is a long-standing goal of neuroscience that promises to
inform the development of new treatments for brain disorders. Early maps of human brain …

Recovery from disorders of consciousness: mechanisms, prognosis and emerging therapies

BL Edlow, J Claassen, ND Schiff… - Nature Reviews Neurology, 2021 - nature.com
Substantial progress has been made over the past two decades in detecting, predicting and
promoting recovery of consciousness in patients with disorders of consciousness (DoC) …

The salience network: a neural system for perceiving and responding to homeostatic demands

WW Seeley - Journal of Neuroscience, 2019 - Soc Neuroscience
The term “salience network” refers to a suite of brain regions whose cortical hubs are the
anterior cingulate and ventral anterior insular (ie, frontoinsular) cortices. This network, which …

Lead-DBS v2: Towards a comprehensive pipeline for deep brain stimulation imaging

A Horn, N Li, TA Dembek, A Kappel, C Boulay, S Ewert… - Neuroimage, 2019 - Elsevier
Deep brain stimulation (DBS) is a highly efficacious treatment option for movement disorders
and a growing number of other indications are investigated in clinical trials. To ensure …

Mapping symptoms to brain networks with the human connectome

MD Fox - New England Journal of Medicine, 2018 - Mass Medical Soc
The Brain Connectome and New Methods of Lesion Analysis Complex neurologic and
psychiatric syndromes cannot be understood on the basis of focal brain lesions. Functional …

Connectivity predicts deep brain stimulation outcome in P arkinson disease

A Horn, M Reich, J Vorwerk, N Li, G Wenzel… - Annals of …, 2017 - Wiley Online Library
Objective The benefit of deep brain stimulation (DBS) for Parkinson disease (PD) may
depend on connectivity between the stimulation site and other brain regions, but which …

Neural circuitry of wakefulness and sleep

TE Scammell, E Arrigoni, JO Lipton - Neuron, 2017 - cell.com
Sleep remains one of the most mysterious yet ubiquitous animal behaviors. We review
current perspectives on the neural systems that regulate sleep/wake states in mammals and …

Are the neural correlates of consciousness in the front or in the back of the cerebral cortex? Clinical and neuroimaging evidence

M Boly, M Massimini, N Tsuchiya… - Journal of …, 2017 - Soc Neuroscience
The role of the frontal cortex in consciousness remains a matter of debate. In this
Perspective, we will critically review the clinical and neuroimaging evidence for the …

Post-stroke deficit prediction from lesion and indirect structural and functional disconnection

A Salvalaggio, M De Filippo De Grazia, M Zorzi… - Brain, 2020 - academic.oup.com
Behavioural deficits in stroke reflect both structural damage at the site of injury, and
widespread network dysfunction caused by structural, functional, and metabolic …

Prospective validation that subgenual connectivity predicts antidepressant efficacy of transcranial magnetic stimulation sites

A Weigand, A Horn, R Caballero, D Cooke, AP Stern… - Biological …, 2018 - Elsevier
Background The optimal target in the dorsolateral prefrontal cortex for treating depression
with repetitive transcranial magnetic stimulation (rTMS) remains unknown. Better efficacy …