This paper is the forty-fifth consecutive installment of the annual anthological review of
research concerning the endogenous opioid system, summarizing articles published during …

Aim This systematic review aims to estimate the relationship between prenatal exposure to
opioids and neurodevelopmental outcomes and examines potential sources of …

Home visiting programs can provide critical support to mothers in recovery from substance
use disorders (SUDs) and young children prenatally exposed to substances. However …

There has been a rapid increase in neonates born with a history of prenatal opioid
exposure. How prenatal opioid exposure affects pain sensitivity in offspring is of interest, as …

Background With significant increases in opioid use/misuse and persistent high prevalence
of prenatal alcohol exposure (PAE), identifying infants at risk for long-term developmental …

Increasing evidence suggests that prenatal exposure to opioids may affect brain
development, but limited data exist on the effects of opioid-exposure on preschool language …

Early adversities, including prenatal drug exposure (PDE) and a negative postnatal
emotional caregiving environment, impact children's long-term development. The protracted …

The current opioid epidemic has dramatically increased the number of children who are
prenatally exposed to opioids, including oxycodone. A number of social and cognitive …

Sex differences are a robust finding in many areas of adult health, including cardiovascular
disease, psychiatric disorders, and chronic pain. However, many sex differences are not …

Understanding of the effects of in utero opioid exposure on neurodevelopment is a priority
given the recent dramatic increase in opioid use among pregnant individuals. However …