Gene-edited babies: What went wrong and what could go wrong
During the second World Summit of Human Gene Editing, Jiankui He presented the gene-
editing project that led to the birth of two baby girls with man-made CC chemokine receptor …
editing project that led to the birth of two baby girls with man-made CC chemokine receptor …
HIV-1 protecting CCR5-Δ32 allele in medieval Poland
P Zawicki, HW Witas - Infection, Genetics and Evolution, 2008 - Elsevier
CCR5-Δ32 is the mutation in the chemokine receptor CCR5 that gives its homozygous
carriers nearly complete protections from HIV-1 infection. Restricted almost exclusively to …
carriers nearly complete protections from HIV-1 infection. Restricted almost exclusively to …
Determination of the CCR5∆ 32 frequency in Emiratis and Tunisians and the screening of the CCR5 gene for novel alleles in Emiratis
SA Al-Jaberi, S Ben-Salem, M Messedi, F Ayadi… - Gene, 2013 - Elsevier
Background The chemokine receptor components play crucial roles in the immune system
and some of them serve as co-receptors for the HIV virus. Several studies have documented …
and some of them serve as co-receptors for the HIV virus. Several studies have documented …
CCR2-64I allele is associated with the progression of AIDS in a Han Chinese population
L Xu, Y Qiao, X Zhang, H Sun, J Wang, D Sun… - Molecular biology …, 2010 - Springer
It has been reported that the CCR5-Delta32, CCR2-64I and SDF1-3′ A polymorphisms
have protective effects against HIV-1 infection and can delay the progression of AIDS in …
have protective effects against HIV-1 infection and can delay the progression of AIDS in …
CCR2 allele polymorphisms in 15 Chinese ethnic populations
XL Zhang, CY Zhang, Y Yu, F Chen… - International journal of …, 2006 - Wiley Online Library
Summary Chemokine receptor‐2 (CCR2) is a co‐receptor for the entry of human
immunodeficiency virus‐1 (HIV‐1) into the target cells. A mutation in CCR2 (CCR2‐64I) …
immunodeficiency virus‐1 (HIV‐1) into the target cells. A mutation in CCR2 (CCR2‐64I) …
Global human genetics of HIV-1 infection and China
TF Zhu, TJ Feng, X Xiao, H Wang, BP Zhou - Cell research, 2005 - nature.com
Genetic polymorphisms in human genes can influence the risk for HIV-1 infection and
disease progression, although the reported effects of these alleles have been inconsistent …
disease progression, although the reported effects of these alleles have been inconsistent …
Identification of HIV-1 specific T lymphocyte responses in highly exposed persistently seronegative Chinese
H Liu, K Hong, MA Jun, Y Lin, LIU Sha… - Chinese medical …, 2006 - journals.lww.com
Background Studies of highly exposed persistently seronegative (HEPS) individuals may
provide valuable information on mechanisms of protection and on vaccine design. Cellular …
provide valuable information on mechanisms of protection and on vaccine design. Cellular …
[PDF][PDF] ЧАСТОТА АЛЛЕЛЕЙ ГЕНА CCR5DELTA32 В САНКТ-ПЕТЕРБУРГЕ
НЕ Любимова, АВ Семёнов - ЖУРНАЛ ИНФЕКТОЛОГИИ - congress-ph.ru
ВИЧ-инфекция продолжает оставаться одной из основных социально-значимых угроз
в сфере здоровья, несмотря на усилия, направленные на борьбу с эпидемией. Хотя …
в сфере здоровья, несмотря на усилия, направленные на борьбу с эпидемией. Хотя …