Procalcitonin: where are we now?

B Hamade, DT Huang - Critical Care Clinics, 2020 - criticalcare.theclinics.com
Procalcitonin (PCT) is a protein that consists of 116 amino acids and is the peptide precursor
of calcitonin. Calcitonin is initially biosynthesized as PCT, which, under normal conditions, is …

Procalcitonin-guided diagnosis and antibiotic stewardship revisited

R Sager, A Kutz, B Mueller, P Schuetz - BMC medicine, 2017 - Springer
Several controlled clinical studies have evaluated the potential of the infection biomarker
procalcitonin (PCT) to improve the diagnostic work-up of patients with bacterial infections …

Diagnostic accuracy of procalcitonin and C-reactive protein for the early diagnosis of intra-abdominal infection after elective colorectal surgery: a meta-analysis

F Cousin, P Ortega-Deballon, A Bourredjem… - Annals of …, 2016 - journals.lww.com
Objective: Intra-abdominal infections (IAIs) after elective colorectal surgery impact
significantly the short-and long-term outcomes. In the era of fast-track surgery, they often …

Defining major surgery: a Delphi consensus among European Surgical Association (ESA) members

D Martin, S Mantziari, N Demartines, M Hübner - World journal of surgery, 2020 - Springer
Background Major surgery is a term frequently used but poorly defined. The aim of the
present study was to reach a consensus in the definition of major surgery within a panel of …

Systematic review of the role of biomarkers in diagnosing anastomotic leakage following colorectal surgery

BU Su'a, HL Mikaere, JL Rahiri… - Journal of British …, 2017 - academic.oup.com
Background Anastomotic leakage (AL) following colorectal surgery can be difficult to
diagnose owing to varying clinical presentations. This systematic review aimed to assess …

Is postoperative decrease of serum albumin an early predictor of complications after major abdominal surgery? A prospective cohort study in a European centre

I Labgaa, GR Joliat, A Kefleyesus, S Mantziari… - BMJ open, 2017 - bmjopen.bmj.com
Objective To test postoperative serum albumin drop (ΔAlb) as a marker of surgical stress
response and early predictor of clinical outcomes. Design Prospective cohort study …

The impact of the type and severity of postoperative complications on long-term outcomes following surgery for colorectal cancer: a systematic review and meta …

ST McSorley, PG Horgan, DC McMillan - Critical reviews in oncology …, 2016 - Elsevier
Background This systematic review investigated the impact of complications by type
(infective vs. non-infective) and severity (using the Clavien Dindo scale) on long-term …

High-risk ileocolic anastomoses for Crohn's disease: when is diversion indicated?

PM Neary, AC Aiello, L Stocchi, S Shawki… - Journal of Crohn's …, 2019 - academic.oup.com
Abstract Background and Aims Patients with Crohn's disease undergoing ileocolectomy and
primary anastomosis are often at increased risk of anastomotic leak. We aimed to determine …

Italian multi-society modified Delphi consensus on the definition and management of anastomotic leakage in colorectal surgery

A Spinelli, G Anania, A Arezzo, S Berti, F Bianco… - Updates in Surgery, 2020 - Springer
Introduction The incidence of anastomotic leak (AL) has not decreased over the past
decades and some important grey areas remain in its definition, prevention, and …

C‐reactive protein as a predictor of anastomotic leak in the first week after anterior resection for rectal cancer

IS Reynolds, MR Boland, F Reilly, A Deasy… - Colorectal …, 2017 - Wiley Online Library
Aim Anastomotic leak (AL) after anterior resection results in increased morbidity, mortality
and local recurrence. The aim of this study was to assess the ability of C‐reactive protein …